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L(+)-Lactic acid

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CAS:79-33-4
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CAS:79-33-4
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CAS:79-33-4
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CAS:79-33-4
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L(+)-Lactic acid Basic information
Background
Product Name:L(+)-Lactic acid
Synonyms:2-HYDROXYPROPIONIC ACID;L-Lactic acid, crystalline, 98.0%+;L-(+)-2-HYDROXYPROPANOIC ACID;L-2-HYDROXYPROPIONIC ACID;SARCOLACTIC ACID;(S)-(+)-LACTIC ACID;(S)-(+)-2-HYDROXYPROPANOIC ACID;(S)-2-HYDROXYPROPIONIC ACID
CAS:79-33-4
MF:C3H6O3
MW:90.08
EINECS:201-196-2
Product Categories:Functional Materials;Hydroxycarboxylic Acids (for High-Performance Polymer Research);Reagent for High-Performance Polymer Research;Intermediates & Fine Chemicals;Pharmaceuticals;Food additive and acidulant;Food additives;bc0001;79-33-4
Mol File:79-33-4.mol
L(+)-Lactic acid Structure
L(+)-Lactic acid Chemical Properties
Melting point 52-54°C
alpha -13.5 º (c=2.5, 1.5N NaOH)
Boiling point 125 °C
density 1.206 g/mL at 25 °C
vapor pressure 0.038Pa at 25℃
FEMA 2611 | LACTIC ACID
refractive index n20/D 1.427
Fp >230 °F
storage temp. 2-8°C
solubility H2O: 10 mg/mL, clear, colorless
form Powder/Solid
pkapK at 25°, 3.79
color White
Odorodorless acidic
PH2.8 (20°C, 10g/L in H2O)
Optical Rotation[α]20/D 13.5°, c = 2.5 in 1.5 M NaOH
Odor Typeodorless
Water Solubility SOLUBLE
Sensitive Hygroscopic
Merck 14,5337
JECFA Number930
BRN 1720251
InChIKeyJVTAAEKCZFNVCJ-REOHCLBHSA-N
LogP-0.54 at 20℃
CAS DataBase Reference79-33-4(CAS DataBase Reference)
NIST Chemistry Reference(s)-2-Hydroxypropanoic acid(79-33-4)
EPA Substance Registry SystemL-Lactic acid (79-33-4)
Safety Information
Hazard Codes Xi,C
Risk Statements 38-41-34-36/37/38-36-35
Safety Statements 26-39-45-36/37/39-36
RIDADR 3261
WGK Germany 1
RTECS OD2800000
3-10
TSCA Yes
HazardClass 8
PackingGroup III
HS Code 29181100
ToxicityLD50 intraperitoneal in mouse: 3194mg/kg
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
L(+)-Lactic acid Usage And Synthesis
Background L-Lactic acid (L(+)-Lactic Acid) is the optically active form of lactic acid and has an (S) stereochemical arrangement.  L-Lactic Acid was first registered as a pesticide 1988 as a plant-growth regulator. There are currently no L-Lactic Acid end-use pesticide products for use as a plant growth regulator.  Animals produce L-Lactate, the conjugate base of lactic acid, from pyruvate via lactate dehydrogenase in fermentation during normal metabolism and exercise. Lactic acid bacteria perform lactic acid fermentation, converting carbohydrates to lactic acid. In humans, lactic acid and its conjugate base are part of many biological processes, from prenatal development to extracellular fluid surrounding neurons. L(+)-lactic acid is a colourless to yellowish, nearly odourless, syrupy liquid with a mild acid taste. It is commercially available as aqueous solutions of various concentrations. These solutions are stable under normal storage conditions.Lactic acid is nontoxic to humans and the environment, but concentrated solutions can cause skin irritation and eye damage. Thus, they must be labelled with a hazard pictogram and related statements. Lactic acid is readily biodegradable.
Chemical PropertiesCrystalline Solid
UsesOccurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, and o
UsesIt is most commonly used for fluid resuscitation after blood loss due to trauma, surgery, or burn injury. It is used in the agricultural, chemical, leather processing, pharmaceuticals, and cosmetics industries, used as an electroplating agent, food/feed additive, pH regulator, cleaning/washing agent, and tanning agent; used to flavor animal feeds; used as a solvent and intermediate in chemical production, as a pH regulator in fabric finishing, and in paints, coatings, soaps, and cleaning products; used to make large scale and fine chemicals, pulp-paper-paper products, food products, and plastic products, in mining, health services, agriculture-forestry-fishing, and building and construction work.
UsesLactic acid has been used:
  • as a component in substrate solution II for lactate dehydrogenase reaction
  • as an additive in storage solution A
  • as a supplement in the artificial gastric juice preparation for evaluation of degree of resistance Lactobacillus to the gastric stresses

DefinitionChEBI: An optically active form of lactic acid having (S)-configuration.
General DescriptionL-(+)-Lactic acid is the only naturally occurring lactic acid in humans and mammals. Commercially, few bacteria like Lactobacillus casei, L. delbrueckii, Streptococcus lactis produces L-Lactic acid by fermentation process. Lactic acid activates hydroxycarboxylic acid receptor, G-protein coupled receptor 81 (GPR81).
Flammability and ExplosibilityNot classified
Biochem/physiol ActionsL-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase.
Purification MethodsPurify lactic acid by fractional distillation at 0.1mm pressure, followed by fractional crystallisation from diethyl ether/isopropyl ether (1:1, dried with sodium). [Borsook et al. J Biol Chem 102 449 1933.] The solvent mixture, *benzene/diethyl ether (1:1) containing 5% pet ether (b 60-80o) has also been used. [Brin Biochemical Preparations 3 61 1953, Beilstein 3 IV 633.]
Tag:L(+)-Lactic acid(79-33-4) Related Product Information
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