TRK-IN-23

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TRK-IN-23 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: 13564774135
Email: marketing@targetmol.com
Products Intro: Product Name:TRK-IN-23
CAS:2924344-29-4
Package:100mg;2500USD|25mg;1520USD|50mg;1980USD
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Email: klq@cw-bio.com
Products Intro: Product Name:TRK-IN-23
CAS:2924344-29-4
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Tel: 010-60605840
Email: psaitong@jm-bio.com
Products Intro: Product Name:TRK-IN-23
CAS:2924344-29-4
Purity:98% Package:5mg
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:TRK-IN-23
CAS:2924344-29-4
Purity:97.01% Package:5mg/RMB 5420;25mg/RMB 11300;50mg/RMB 15200

TRK-IN-23 manufacturers

  • TRK-IN-23
  • TRK-IN-23 pictures
  • $2700.00
  • 2026-07-17
  • CAS:2924344-29-4
  • Purity: 97.01%
  • Supply Ability: 10g
TRK-IN-23 Basic information
Product Name:TRK-IN-23
Synonyms:TRK-IN-23;2H-Indol-2-one, 5-[[(5-fluoro-2-methoxyphenyl)methyl]amino]-1,3-dihydro-3-(1H-imidazol-5-ylmethylene)-, (3Z)-
CAS:2924344-29-4
MF:C20H17FN4O2
MW:364.37
EINECS:
Product Categories:
Mol File:2924344-29-4.mol
TRK-IN-23 Structure
TRK-IN-23 Chemical Properties
Boiling point 683.329±55.00 °C(Press: 760.00 Torr)(predicted)
density 1.408±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka12.246±0.10(predicted)
Safety Information
MSDS Information
TRK-IN-23 Usage And Synthesis
UsesTRK-IN-23 (compound 24b) is a potent and orally active TRK inhibitor with IC50 values of 0.5 nM, 9 nM, 14 nM, 4.4 nM, and 4.8 nM against TRKA, TRKC, TRKAG595R, TRKAF589L, and TRKAG667C, respectively. TRK-IN-23 indues apoptosis of Ba/F3-TRKAG595Rand Ba/F3-TRKAG667C cells[1].
IC 50TrkA: 0.5 nM (IC50); TrkC: 9 nM (IC50); TRKAG595R: 14 nM (IC50); TRKAF589L: 4.4 nM (IC50); TRKAG667C: 4.8 nM (IC50)
References[1] Qiaohua Qin, et al. Design, synthesis and biological evaluation of novel indolin-2-one derivatives as potent second-generation TRKs inhibitors. Eur J Med Chem. 2023 May 5;253:115291. DOI:10.1016/j.ejmech.2023.115291
TRK-IN-23 Preparation Products And Raw materials
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