Thieno[2,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-, (9Z,12Z)-9,12-octadecadien-1-yl ester

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Thieno[2,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-, (9Z,12Z)-9,12-octadecadien-1-yl ester Basic information
Product Name:Thieno[2,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-, (9Z,12Z)-9,12-octadecadien-1-yl ester
Synonyms:Thieno[2,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-, (9Z,12Z)-9,12-octadecadien-1-yl ester
CAS:2921586-65-2
MF:C44H72N2O3S
MW:709.12
EINECS:
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Mol File:2921586-65-2.mol
Thieno[2,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-, (9Z,12Z)-9,12-octadecadien-1-yl ester Structure
Thieno[2,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-, (9Z,12Z)-9,12-octadecadien-1-yl ester Chemical Properties
Boiling point 800.5±65.0 °C(predicted)
density 0.996±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
solubility Ethanol: Soluble: = 10 mg/ml
pka14.10±0.20(predicted)
Safety Information
MSDS Information
Thieno[2,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-, (9Z,12Z)-9,12-octadecadien-1-yl ester Usage And Synthesis
DescriptionLipid 20b is a thiophene ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.1 LNPs containing lipid 20b and encapsulating mRNA encoding a luciferase reporter induce bioluminescence in the lungs, spleen, and retina of mice.WARNING This product is not for human or veterinary use.
References[1] YULIA EYGERIS. Thiophene-based lipids for mRNA delivery to pulmonary and retinal tissues.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 11: e2307813120. DOI: 10.1073/pnas.2307813120
Thieno[2,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-, (9Z,12Z)-9,12-octadecadien-1-yl ester Preparation Products And Raw materials
Tag:Thieno[2,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-, (9Z,12Z)-9,12-octadecadien-1-yl ester(2921586-65-2) Related Product Information
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