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| | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Basic information |
| Product Name: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | | Synonyms: | 3-SN-PHOSPHATIDYLCHOLINE, 1,2-DIOLEOYL;1,2-DI9-CIS-OCTADECENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1,2-DI(CIS-9-OCTADECENOYL)-SN-GLYCERO-3-PHOSPHOCHOLINE;1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE;1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;18:1 PC (CIS);Dierucoyl phosphatidylcholine;COATSOME MC-8181 (DOPC) | | CAS: | 4235-95-4 | | MF: | C44H84NO8P | | MW: | 786.12 | | EINECS: | 224-193-8 | | Product Categories: | | | Mol File: | 4235-95-4.mol |  |
| | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties |
| Melting point | -21 °C | | storage temp. | -20°C | | solubility | Chloroform (Slightly, Sonicated), Methanol (Slightly) | | form | solution | | color | White to Off-White | | biological source | synthetic (organic) | | BRN | 3898070 | | Stability: | Hygroscopic, Light Sensitive | | InChIKey | SNKAWJBJQDLSFF-NVKMUCNASA-N | | SMILES | [C@H](OC(=O)CCCCCCC/C=C\CCCCCCCC)(COP([O-])(=O)OCC[N+](C)(C)C)COC(=O)CCCCCCC/C=C\CCCCCCCC |&1:0,r| | | CAS DataBase Reference | 4235-95-4 |
| | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Usage And Synthesis |
| Description | DOPC, also known as 18:1 (?9-Cis) PC, is a phospholipid containing the unsaturated long-chain (18:1) oleic acid inserted at the sn-1 and sn-2 positions. It is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes. | | Chemical Properties | Amorphous white powder | | Uses | 1,2-Dioleoyl-sn-glycero-3-phosphocholine is a phospholipid containing the unsaturated long-chain (18:1) oleic acid inserted at the sn-1 and sn-2 positions. It is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes. | | Uses | 1,2-Dioleoyl-sn-glycero-3-phosphocholine has been used for the reconstitution of proteoliposome (PL). It has also been used in the preparation of lipid vesicles. | | Uses | 18:1 (Δ9-Cis) PC (DOPC) has been used for reproducing the supramolecular structure of the synovial fluid. It may also be used in the liposome preparation and in the preparation of planar supported membranes. | | Definition | ChEBI: 1,2-dioleoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine 36:2 in which the phosphatidyl acyl groups at positions 1 and 2 are both oleoyl. It is a 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine betaine and a 1,2-di-octadecenoyl-sn-glycero-3-phosphocholine. It is functionally related to an oleic acid. It is a conjugate base of a 1,2-dioleoyl-sn-glycero-3-phosphocholine(1+). | | General Description | The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis. | | Biochem/physiol Actions | 18:1 (Δ9-Cis) PC (DOPC) shows high resistance to the toxic effects of dimethyl sulfoxide (DMSO). |
| | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials |
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