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Hexadecanoic acid-1-13C manufacturers
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| | Hexadecanoic acid-1-13C Basic information |
| Product Name: | Hexadecanoic acid-1-13C | | Synonyms: | PALMITIC-1-13C ACID;PALMITIC ACID (1-13C);Hexadecanoic acid-1-13C,(Palmitic-1-13C acid),99 atom % 13C;HexadecanoicacidpalmiticCacidatomC;PALMITIC-1-13C ACID, 99 ATOM % 13C;PALMITIC ACID 98%(RG);Hexadecanoic Acid-13C;Palmitic Acid-13C (C1 labeled) | | CAS: | 57677-53-9 | | MF: | C16H32O2 | | MW: | 257.43 | | EINECS: | | | Product Categories: | Fatty Acids 13C & 2H | | Mol File: | 57677-53-9.mol |  |
| | Hexadecanoic acid-1-13C Chemical Properties |
| Melting point | 61-64 °C(lit.) | | Boiling point | 271.5 °C100 mm Hg(lit.) | | density | 0.855 g/mL at 25 °C | | storage temp. | Store at -20°C | | solubility | DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:2): 0.25 mg/ml | | form | A solid | | color | White to off-white | | InChI | 1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)/i16+1 | | InChIKey | IPCSVZSSVZVIGE-LOYIAQTISA-N | | SMILES | CCCCCCCCCCCCCCC[13C](O)=O | | CAS Number Unlabeled | 57-10-3 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | Hexadecanoic acid-1-13C Usage And Synthesis |
| Description | Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively. Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellular proteins, promotes protein-vesicle interactions, and regulates various G protein-coupled receptor functions. Red blood cell palmitic acid levels are increased in patients with metabolic syndrome compared to patients without metabolic syndrome and are also increased in the plasma of patients with type 2 diabetes compared to individuals without diabetes. | | Uses | Hexadecanoic-1-13C Acid is a labeled analog of Palmitic Acid (P144500), which is a common fatty acid found in plants and animals. The body converts excess carbohydrates into Palmitic Acid, thus Palmitic Acid is the first fatty acid produced during fatty acid synthesis as well as a precursor for longer fatty acids. | | References | [1] SARWAT FATIMA. Palmitic acid is an intracellular signaling molecule involved in disease development.[J]. Cellular and Molecular Life Sciences, 2019, 76 13: 2547-2557. DOI: 10.1007/s00018-019-03092-7
[2] M J SANTOS. Influence of dietary supplementation with fish on plasma fatty acid composition in coronary heart disease patients.[J]. Annals of Nutrition and Metabolism, 1995, 39 1: 52-62. DOI: 10.1159/000177842
[3] LUN-ZHAO YI. Plasma fatty acid metabolic profiling and biomarkers of type 2 diabetes mellitus based on GC/MS and PLS-LDA[J]. FEBS Letters, 2006, 580 30: 6837-6845. DOI: 10.1016/j.febslet.2006.11.043
[4] EDMOND K KABAGAMBE. Erythrocyte fatty acid composition and the metabolic syndrome: a National Heart, Lung, and Blood Institute GOLDN study.[J]. Clinical chemistry, 2008: 154-162. DOI: 10.1373/clinchem.2007.095059 |
| | Hexadecanoic acid-1-13C Preparation Products And Raw materials |
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