- Isobutyrophenone
-
- $99.00/ kg
-
2025-05-23
- CAS:611-70-1
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20ton
- Isobutyrophenone
-
- $15.00 / 1KG
-
2021-08-12
- CAS:611-70-1
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Isobutyrophenone
-
- $1.00 / 1g
-
2020-01-13
- CAS:611-70-1
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 10000KGS
|
| | Isobutyrophenone Basic information |
| Product Name: | Isobutyrophenone | | Synonyms: | PHENYL ISOPROPYL KETONE;Isobutyrophenone 97%;ALPHA-METHYLPROPIOPHENONE;2-METHYL-1-PHENYL-1-PROPANONE;ISOBUTYROPHENONE;ISOBUTYRYLBENZENE;ISOPROPYL PHENYL KETONE;Isobutyrophenone, 97% 25GR | | CAS: | 611-70-1 | | MF: | C10H12O | | MW: | 148.2 | | EINECS: | 210-275-0 | | Product Categories: | | | Mol File: | 611-70-1.mol |  |
| | Isobutyrophenone Chemical Properties |
| Melting point | 1 °C | | Boiling point | 217 °C (lit.) | | density | 0.988 g/mL at 25 °C (lit.) | | vapor pressure | 1 mm Hg ( 50 °C) | | refractive index | n20/D 1.517(lit.) | | Fp | 184 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Sparingly), Methanol (Slightly) | | form | Oil | | color | Colourless | | Water Solubility | immiscible | | BRN | 774499 | | Henry's Law Constant | 5.7×10-1 mol/(m3Pa) at 25℃, Zhang et al. (2010) | | InChI | 1S/C10H12O/c1-8(2)10(11)9-6-4-3-5-7-9/h3-8H,1-2H3 | | InChIKey | BSMGLVDZZMBWQB-UHFFFAOYSA-N | | SMILES | CC(C)C(=O)c1ccccc1 | | LogP | 2.73 | | CAS DataBase Reference | 611-70-1(CAS DataBase Reference) | | NIST Chemistry Reference | Isopropyl phenyl ketone(611-70-1) | | EPA Substance Registry System | 1-Propanone, 2-methyl-1-phenyl- (611-70-1) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | TSCA | TSCA listed | | HS Code | 29143900 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Acute Tox. 4 Oral |
| | Isobutyrophenone Usage And Synthesis |
| Chemical Properties | clear colorless to very slightly yellow liquid | | Uses | Isobutyrophenone is used as an internal standard in the determination of hydroxyzine hydrochloride and benzyl alcohol in injection solutions. It is also used in the preparation of alpha-hydroxyisobutyrophenone. Isobutyrophenone is employed as photosensitizer intermediate. It can react with bromoacetic acid ethyl ester to get 3-hydroxy-4-methyl-3-phenyl-valeric acid ethyl ester. | | Preparation | Isobutyrophenone synthesis: Benzene underwent a Friedel–Crafts acylation with isobutyryl chloride to synthesize isobutyrophenone. The reaction was performed using excess benzene as a replacement for a typical solvent and heat to reflux (88 °C) for a period of 3 hours. Any unreacted benzene was recovered after the reaction during the distillation process. A 66 % yield of isobutyrophenone was obtained from the solar synthesis, compared to a 44 % yield from an in-lab, electrical heating analysis.
 | | Synthesis Reference(s) | Journal of the American Chemical Society, 71, p. 1061, 1949 DOI: 10.1021/ja01171a084
The Journal of Organic Chemistry, 32, p. 404, 1967 DOI: 10.1021/jo01288a032
Tetrahedron Letters, 14, p. 2491, 1973 | | Flammability and Explosibility | Non flammable |
| | Isobutyrophenone Preparation Products And Raw materials |
|