1,1'-Diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl[9,9'-bianthracene]-4,4'(1H,1'H)-dione

1,1'-Diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl[9,9'-bianthracene]-4,4'(1H,1'H)-dione Suppliers list
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1,1'-Diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl[9,9'-bianthracene]-4,4'(1H,1'H)-dione manufacturers

  • Setomimycin
  • Setomimycin pictures
  • $198.00
  • 2026-07-27
  • CAS:69431-87-4
  • Purity: 92.81%
  • Supply Ability: 10g
1,1'-Diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl[9,9'-bianthracene]-4,4'(1H,1'H)-dione Basic information
Product Name:1,1'-Diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl[9,9'-bianthracene]-4,4'(1H,1'H)-dione
Synonyms:1,1'-Diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl[9,9'-bianthracene]-4,4'(1H,1'H)-dione;A-39183B;Antibiotic A-39183B;Setomimycin;SetoMiMycin [SetoMiMicin];AM 2947;AM2947;AM-2947
CAS:69431-87-4
MF:C34H28O9
MW:580.58
EINECS:
Product Categories:
Mol File:69431-87-4.mol
1,1'-Diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl[9,9'-bianthracene]-4,4'(1H,1'H)-dione Structure
1,1'-Diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl[9,9'-bianthracene]-4,4'(1H,1'H)-dione Chemical Properties
Boiling point 765.2±60.0 °C(Predicted)
density 1.479±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Chloroform: soluble; DMSO: soluble
form A solid
pka3.61±0.60(Predicted)
Safety Information
MSDS Information
1,1'-Diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl[9,9'-bianthracene]-4,4'(1H,1'H)-dione Usage And Synthesis
UsesSetomimycin is a rare 9,9’-bianthryl antibiotic first isolated from a strain of Streptomyces pseudovenezuelae by Omura and colleagues at the Kitasato Institute, Japan, in 1978. Setomimycin is active against Gram positive bacteria, including mycobacteria, and has antitumor activity both in vitro and in vivo. Limited access has restricted further research on this metabolite.
UsesSetomimycin is an antibiotic that is active against Gram positive bacteria, including mycobacteria.
in vivo

Setomimycin (20 mg/kg; i.p.; alternate days for two weeks) shows antitumor activity in mice[2].
Pharmacokinetic Parameters of Setomimycin in female BALB/c mice[2].

Pharmacokinetic parametersValue
Cmax (ng/ml)694 ± 62
Tmax (h)0.3 ± 0.1
T1/2 (h)2.3 ± 0.5
AUC0-t (ng.h/mL)2613 ± 111
AUC0-α (ng.h/mL)2734 ± 108
Vd (L/Kg)24 ± 4
Cl (L/h/Kg)7.4 ± 0.3
Female BALB/c mice, 20 mg/kg ip (1 % DMSO +30 % PEG-200 + 2 % Tween 80 + q.s. water (v/v))[2]
Animal Model:6 weeks, 25-30 g, female BALB/c mice (4T1 cells)[2]
Dosage:20 mg/kg
Administration:I.p.; every other day for two weeks
Result:Decreased primary tumor weight (76%) and volume (90.5%).
1,1'-Diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl[9,9'-bianthracene]-4,4'(1H,1'H)-dione Preparation Products And Raw materials
Tag:1,1'-Diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl[9,9'-bianthracene]-4,4'(1H,1'H)-dione(69431-87-4) Related Product Information
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