(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE

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(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE Suppliers list
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:J 104129 fumarate
CAS:244277-89-2
Package:10 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
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Products Intro: Product Name:J-104129
CAS:244277-89-2
Purity:NLT 98% Remarks:MC543873
Company Name: Aladdin Scientific
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Products Intro: Product Name:J 104129 fumarate
CAS:244277-89-2
Purity:>=99% Package:$204.9/10mg;Bulk package Remarks:99%
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:J 104129 fumarate
CAS:244277-89-2
Package:100mg;2500USD|50mg;1980USD|25mg;1520USD
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
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Products Intro: Product Name:J 104129 fuMarate;(αR)-α-Cyclopentyl-α-hydroxy-N-[1-(4-Methyl-3-pentenyl)-4-piperidinyl]benzeneacetaMidefuMarate
CAS:244277-89-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g

(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE manufacturers
(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE Basic information
Product Name:(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE
Synonyms:(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE;J 104129 FUMARATE;(αR)-α-Cyclopentyl-α-hydroxy-N-[1-(4-methyl-3-pentenyl)-4-piperidinyl]benzeneacetamidefumarate;Benzeneacetamide, α-cyclopentyl-α-hydroxy-N-[1-(4-methyl-3-penten-1-yl)-4-piperidinyl]-, (αR)-
CAS:244277-89-2
MF:C24H36N2O2
MW:384.55
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Mol File:244277-89-2.mol
(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE Structure
(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE Chemical Properties
storage temp. Store at +4°C
solubility <50.06mg/ml in DMSO; <25.03mg/ml in ethanol
Safety Information
MSDS Information
(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE Usage And Synthesis
UsesJ 104129 is a mAChR M3 antagonist.
Biological ActivityPotent M 3 muscarinic receptor antagonist that displays ~ 120-fold selectivity over M 2 receptors (K i values are 4.2, 19 and 490 nM for human M 3 , M 1 and M 2 receptors respectively). Exhibits > 250-fold bronchial selectivity; inhibits ACh-induced bronchoconstriction but not ACh-induced bradycardia (K B values are 3.3 and 170 nM for rat trachea M 3 and rat right atria M 2 receptors respectively).
in vivo

J-104129 (10 mg/kg; p.o.; single) shows durable bronchodilatory action lasting over 10 h in rats[1][2].
J-104129 (p.o.) antagonizes ACh-induced bronchoconstriction with an ED50 value of 0.58 mg/kg in rats[1].

Animal Model:Male Sprague-Dawley rats[1][2].
Dosage:10 mg/kg
Administration:Oral administration; single.
Result:Exhibited bronchodilatory activity.
(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE Preparation Products And Raw materials
Tag:(AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE(244277-89-2) Related Product Information
(2-CYCLOPENTYL-2-PHENYLETHYL)AMINE (AR)-A-CYCLOPENTYL-A-HYDROXY-N-[1-(4-METHYL-3-PENTENYL)-4-PIPERIDINYL]BENZENEACETAMIDE FUMARATE