| Company Name: |
Cool Pharm, Ltd |
| Tel: |
021-58581007 18019463053 |
| Email: |
sales@coolpharm.com |
|
| | 2-Amino-3-nitro-benzaldehyde Basic information |
| | 2-Amino-3-nitro-benzaldehyde Chemical Properties |
| Melting point | 137-138 °C(Solv: methanol (67-56-1)) | | Boiling point | 335.8±32.0 °C(Predicted) | | density | 1.441±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | -3.97±0.25(Predicted) | | Appearance | Yellow to brown Solid |
| | 2-Amino-3-nitro-benzaldehyde Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 2-amino-3-nitrobenzaldehyde from (2-amino-3-nitrophenyl)methanol: Synthesis of 6,7-didehydro-17-methyl-8'-nitroquinolo[2',3':6,7]morphinan-3,14β-diol hydrochloride (SYK-349) from compound 29d with reference to the procedure used for the preparation of SYK-27. The product is a brown amorphous solid with 98% yield and a melting point of 255-262°C (decomposition). Elemental analysis (C24H23N3O4-1.5HCl-0.5H2O) Calculated values: C, 59.91; H, 5.34; N, 8.73. Measured values: C, 60.10; H, 5.42; N, 8.46. | | References | [1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 19, p. 5810 - 5831 |
| | 2-Amino-3-nitro-benzaldehyde Preparation Products And Raw materials |
|