| Company Name: |
YantaiBio |
| Tel: |
13758194781; 13758194781 |
| Email: |
764619768@qq.com |
| Company Name: |
Fuan Bio |
| Tel: |
15002819872 |
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2845971812@qq.com |
|
| | Skf 107457 Basic information |
| Product Name: | Skf 107457 | | Synonyms: | 5-(L-Alanyl-L-alanylamino)-4-hydroxy-6-phenylhexanoic acid, methyl valyl-valyl amide;Aids000504;Aids-000504;Ala-Ala-Phe.psi.[ch(OH)ch2]Gly-Val-val-och3;L-Valine, L-alanyl-L-alanyl-(.gamma.S, .delta.S)-.delta.-amino-.gamma.-hydroxybenzenehexanoyl-L-valyl-, methyl ester;L-Valine, L-alanyl-L-alanyl-(γS,δS)-δ-amino-γ-hydroxybenzenehexanoyl-L-valyl-, methyl ester | | CAS: | 126333-28-6 | | MF: | C29H47N5O7 | | MW: | 577.72 | | EINECS: | | | Product Categories: | | | Mol File: | 126333-28-6.mol |  |
| | Skf 107457 Chemical Properties |
| Boiling point | 897.8±65.0 °C(Predicted) | | density | 1.154±0.06 g/cm3(Predicted) | | pka | 13.28±0.46(Predicted) |
| | Skf 107457 Usage And Synthesis |
| Description | SKF-107457 is a HIV protease type 1 inhibitor, and are hexapeptide substrate analogues with the scissile bond being replaced by a hydroxyethylene isostere. | | Uses | SKF107457 is an HIV-1 protease inhibitor that can be used in AIDS research[1][2]. | | References | [1] Verkhivker GM. Empirical free energy calculations of human immunodeficiency virus type 1 protease crystallographic complexes. II. Knowledge-based ligand-protein interaction potentials applied to thermodynamic analysis of hydrophobic mutations. Pac Symp Biocomput. 1996:638-52. PMID:9390264
[2] Fitzgerald P M D. HIV protease-ligand complexes: Current Opinion in Structural Biology 1993, 3: 868–874[J]. Current Opinion in Structural Biology, 1993, 3(6): 868-874. |
| | Skf 107457 Preparation Products And Raw materials |
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