CAY10602

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Company Name: ATK CHEMICAL COMPANY LIMITED
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Products Intro: Product Name:CAY 10602
CAS:374922-43-7
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:CAY10602
CAS:374922-43-7
Purity:98.87% Package:5mg;47USD|10mg;57USD|25mg;97USD Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:CAY10602
CAS:374922-43-7
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Company Name: InvivoChem
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Products Intro: Product Name:CAY10602
CAS:374922-43-7
Purity:98% Package:25mg Remarks:V2358
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:CAY10602
CAS:374922-43-7
Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；200 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

CAY10602 manufacturers

  • CAY10602
  • CAY10602 pictures
  • $30.00
  • 2026-04-21
  • CAS:374922-43-7
  • Purity: 98.92%
  • Supply Ability: 10g
CAY10602 Basic information
Product Name:CAY10602
Synonyms:CAY10602;1-(4-Fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine;SIRT1 Activator II - CAS 374922-43-7 - Calbiochem;CAY10602, >98%;1H-Pyrrolo[2,3-b]quinoxalin-2-amine, 1-(4-fluorophenyl)-3-(phenylsulfonyl)-;CAY10602 HCl;Inhibitor,CAY 10602,CAY10602,CAY-10602,inhibit,Sirtuin;CAY10602, SIRT1 Activator
CAS:374922-43-7
MF:C22H15FN4O2S
MW:418.44
EINECS:
Product Categories:
Mol File:374922-43-7.mol
CAY10602 Structure
CAY10602 Chemical Properties
Melting point 270 °C
storage temp. +2C to +8C
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
form Off-white powder
color Light yellow to Amber to Dark green
InChI1S/C22H15FN4O2S/c23-14-10-12-15(13-11-14)27-21(24)20(30(28,29)16-6-2-1-3-7-16)19-22(27)26-18-9-5-4-8-17(18)25-19/h1-13H,24H2
InChIKeyCSFVFDHRYKBBPD-UHFFFAOYSA-N
SMILESFC(C=C1)=CC=C1N2C(N)=C(S(C3=CC=CC=C3)(=O)=O)C4=C2N=C5C(C=CC=C5)=N4
CAS DataBase Reference374922-43-7
Safety Information
WGK Germany WGK 2
HS Code 2933.99.8290
Storage Class11 - Combustible Solids
MSDS Information
CAY10602 Usage And Synthesis
UsesCAY10602 is a SIRT1 activator. CAY10602 dose-dependently suppresses the NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells[1].
General DescriptionA cell-permeable pyrroloquinoxaline compound that acts as a reversible SIRT1 activator (10 μM causes ~2.3-fold fluorescent enhancement in a fluorescent assay using hrSIRT1) and enhances fat mobilization in fully differentiated 3T3L1 fibroblasts. Shown to inhibit LPS-induced TNF-α release in THP-1 cells by ~10-fold more potent than resveratrol (Cat. No. 554325).
IC 50SIRT1
References[1] Nayagam VM, et al. SIRT1 modulating compounds from high-throughput screening as anti-inflammatory and insulin-sensitizing agents. J Biomol Screen. 2006 Dec;11(8):959-67. DOI:10.1177/1087057106294710
CAY10602 Preparation Products And Raw materials
Tag:CAY10602(374922-43-7) Related Product Information
CAY10602 1-[(4-fluorophenyl)methyl]-3-(3-methylphenyl)sulfonylpyrrolo[3,2-b]quinoxalin-2-amine SRT2104 (GSK2245840) Resveratrol BUTEIN SIRT1 ACTIVATOR 3