| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 400-920-5774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:KOdiA-PC
CAS:439904-33-3
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:KOdiA-PC
CAS:439904-33-3
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
KOdiA-PC manufacturers
- KOdiA-PC
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- $2560.00
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2026-07-27
- CAS:439904-33-3
- Purity:
- Supply Ability: 10g
- KOdiA-PC
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2026-07-01
- CAS:439904-33-3
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 20Tons
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| | KOdiA-PC Basic information |
| Product Name: | KOdiA-PC | | Synonyms: | KOdiA-PC;KOdiA-PC Exclusive;PEZXEQJZQAVYCZ-NLMPBQEBSA-N | | CAS: | 439904-33-3 | | MF: | C32H58NO11P | | MW: | 663.79 | | EINECS: | | | Product Categories: | | | Mol File: | 439904-33-3.mol |  |
| | KOdiA-PC Chemical Properties |
| storage temp. | Store at -80°C, protect from light | | solubility | DMF: .5 mg/ml; DMSO: .5 mg/ml; Ethanol: 30 mg/ml; PBS (pH7.2): 5 mg/ml | | form | Liquid | | color | Colorless to light yellow |
| | KOdiA-PC Usage And Synthesis |
| Description | Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic.1 Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position.2 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl) phosphatidylcholine, or KOdiA-PC, is one of the most potent CD36 ligands among the oxLDL species.3 KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle, and may be one of the more important structural determinants of oxLDL. | | Uses | Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL. | | Definition | ChEBI: PKODiA-PC is a 1,2-diacyl-sn-glycero-3-phosphocholine. | | References | 1. Podrez, E.A., Febbraio, M., Sheibani, N., et al. Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species J. Clin. Invest. 105(8),1095-1108(2000).
2. Podrez, E.A., Poliakov, E., Shen, Z., et al. A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions J. Biol. Chem. 277(41),38517-38523(2002).
3. Podrez, E.A., Poliakov, E., Shen, Z., et al. Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36 J. Biol. Chem. 277(41),38503-38516(2002). |
| | KOdiA-PC Preparation Products And Raw materials |
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