Z-Leu-Leu-Tyr-a-keto aldehyde

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Z-Leu-Leu-Tyr-a-keto aldehyde Basic information
Product Name:Z-Leu-Leu-Tyr-a-keto aldehyde
Synonyms:Z-Leu-Leu-Tyr-a-keto aldehyde;L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-[(4-hydroxyphenyl)methyl]-2,3-dioxopropyl]-;Z-Leu-Leu-Tyr-α-keto aldehyde
CAS:204649-66-1
MF:C30H39N3O7
MW:553.65
EINECS:
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Mol File:204649-66-1.mol
Z-Leu-Leu-Tyr-a-keto aldehyde Structure
Z-Leu-Leu-Tyr-a-keto aldehyde Chemical Properties
Boiling point 813.3±65.0 °C(Predicted)
density 1.188±0.06 g/cm3(Predicted)
pka9.82±0.15(Predicted)
Sequence{Cbz}-Leu-Leu-Tyr-{COCHO}
Safety Information
MSDS Information
Z-Leu-Leu-Tyr-a-keto aldehyde Usage And Synthesis
UsesZ-Leu-Leu-Tyr-COCHO is a potent chymotrypsin-like activity inhibitor with a Ki value of 3.0 nM[1].
References[1] Lynas JF, et, al. Inhibitors of the chymotrypsin-like activity of proteasome based on di- and tri-peptidyl alpha-keto aldehydes (glyoxals). Bioorg Med Chem Lett. 1998 Feb 17;8(4):373-8. DOI:10.1016/s0960-894x(98)00030-4
Z-Leu-Leu-Tyr-a-keto aldehyde Preparation Products And Raw materials
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