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| | 2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID Basic information |
| Product Name: | 2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID | | Synonyms: | Benzeneaceticacid,α-aMino-4-Methyl-;2-amino-2-p-tolylacetic acid;4-Methylphenyl glycin;2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID;4-METHYLPHENYL GLYCINE;AMINO-P-TOLYL-ACETIC ACID;DL-4-METHYLPHENYLGLYCINE;RARECHEM AK ML 0528 | | CAS: | 13227-01-5 | | MF: | C9H11NO2 | | MW: | 165.19 | | EINECS: | | | Product Categories: | pharmacetical | | Mol File: | 13227-01-5.mol |  |
| | 2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID Chemical Properties |
| Melting point | 256-257° | | Boiling point | 306.8±30.0 °C(Predicted) | | density | 1.200±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Acetonitrile: Slightly soluble: 0.1-1 mg/ml | | form | solid | | pka | 2.03±0.10(Predicted) | | color | White | | CAS DataBase Reference | 13227-01-5(CAS DataBase Reference) |
| HazardClass | IRRITANT | | HS Code | 2922498590 |
| | 2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID Usage And Synthesis |
| Uses | 2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI)[1][2]. | | References | [1] Kalie A M, et al. Cytosolic Delivery of Proteins by Bioreversible Esterification. JAmChem. 2017. 139(41):14396–14398. [2] Finlay MRV, et al. Preparation of 1,3,4-thiadiazole compounds and their use in treating cancer: World Intellectual Property Organization, WO2017093301[P]. 2017-06-08. [3] JERZY ZOŃ Roman G Nikolaus Amrhein. Inhibitors of phenylalanine ammonia-lyase: 1-aminobenzylphosphonic acids substituted in the benzene ring[J]. Phytochemistry, 2002, 59 1: Pages 9-21. DOI: 10.1016/s0031-9422(01)00425-3 |
| | 2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID Preparation Products And Raw materials |
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