|
|
| | Flubromazepam Basic information | | Uses |
| | Flubromazepam Chemical Properties |
| Melting point | 189-190℃ | | Boiling point | 465.7±45.0 °C(Predicted) | | density | 1.58±0.1 g/cm3(Predicted) | | solubility | DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml; Methanol: 1 mg/ml | | form | A crystalline solid | | pka | 11.55±0.70(Predicted) | | CAS DataBase Reference | 2647-50-9 |
| | Flubromazepam Usage And Synthesis |
| Uses | Flubromazepam is a designer benzodiazepine drug structurally related to Phenazepam ; a drug used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal and insomnia. Phenazepam can also be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety.
Flubromazepam is a potent, long-acting novel psychoactive benzodiazepine with anxiolytic, anticonvulsant, muscle relaxant and hypnotic properties. Flubromazepam reportedly has a high addiction potential and risk of overdose. This certified Snap-N-Spike® solution is suitable for use as a starting material in calibrators and controls for numerous GC/MS or LC/MS applications in forensic analysis, clinical toxicology and urine drug testing.
| | Description | Flubromazepam (Item No. 15157) is an analytical reference standard categorized as a benzodiazepine. Flubromazepam has been detected in seized samples and has anxiolytic and sedative properties. This product is intended for research and forensic applications. | | Uses | Flubromazepam is a designer benzodiazepine drug structurally related to Phenazepam (P295300); a drug used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal and insomnia. Phenazepam (P295300) can also be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety. | | References | [1] BJOERN MOOSMANN. Detection and identification of the designer benzodiazepine flubromazepam and preliminary data on its metabolism and pharmacokinetics[J]. Journal of Mass Spectrometry, 2013, 48 11: 1150-1159. DOI: 10.1002/jms.3279
[2] JONES L E, STEWART A, PETERS K L, et al. Infrared and Raman screening of seized novel psychoactive substances: a large scale study of >200 samples[J]. Analyst, 2016, 3: 902-909. DOI: 10.1039/c5an02326b
[3] RACHELLE ABOUCHEDID. Assessment of the Availability, Cost, and Motivations for Use over Time of the New Psychoactive Substances-Benzodiazepines Diclazepam, Flubromazepam, and Pyrazolam-in the UK.[J]. Journal of Medical Toxicology, 2018, 14 2: 134-143. DOI: 10.1007/s13181-018-0659-3 |
| | Flubromazepam Preparation Products And Raw materials |
|