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| | 1-Methyl-2-nonylquinolin-4(1H)-one Basic information |
| Product Name: | 1-Methyl-2-nonylquinolin-4(1H)-one | | Synonyms: | 1-Methyl-2-nonylquinolin-4(1H)-one;1-Methyl-2-n-nonyl-4(1H) quinolone;1-Methyl-2-nonyl-4-quinolinone;1-METHYL-2-NONYLQUINOLIN-4(1H)-O;4(1H)-Quinolinone, 1-methyl-2-nonyl-;1-Methyl-2-nonyl-4(1H)-quinolinone;1-methyl-2-nonylquinolin-4-one;N-methyl-2-nonyl-4-quinolone | | CAS: | 68353-24-2 | | MF: | C19H27NO | | MW: | 285.42 | | EINECS: | | | Product Categories: | | | Mol File: | 68353-24-2.mol |  |
| | 1-Methyl-2-nonylquinolin-4(1H)-one Chemical Properties |
| Melting point | 73-75℃ | | Boiling point | 391.9±42.0 °C(Predicted) | | density | 0.990±0.06 g/cm3(Predicted) | | pka | 2.53±0.70(Predicted) |
| | 1-Methyl-2-nonylquinolin-4(1H)-one Usage And Synthesis |
| Uses | 1-Methyl-2-nonyl-4(1H)-quinolone, a quinolone alkaloid, is a potent and selective MAO-B (monoamine oxidase) inhibitor. 1-Methyl-2-nonyl-4(1H)-quinolone exhibites inhibitory activity on leukotriene biosynthesis, with an IC50 of 12.1 μM[1][2]. | | Definition | ChEBI: 1-Methyl-2-nonyl-4(1H)-quinolinone is a member of quinolines. | | IC 50 | MAO-B; MAO-A | | References | [1] Han XH, et al. Quinolone alkaloids from evodiae fructus and their inhibitory effects on monoamine oxidase. Arch Pharm Res. 2007 Apr;30(4):397-401. DOI:10.1007/BF02980210
[2] Adams M, et al. Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa. Planta Med. 2004 Oct;70(10):904-8. DOI:10.1055/s-2004-832614 |
| | 1-Methyl-2-nonylquinolin-4(1H)-one Preparation Products And Raw materials |
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