- Propargyl-PEG6-COOtBu
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2026-02-05
- CAS:1355197-95-3
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
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| | Propargyl-PEG6-t-butyl ester Basic information |
| Product Name: | Propargyl-PEG6-t-butyl ester | | Synonyms: | Propargyl-PEG6-COOtBu;Propargyl-PEG6-t-butyl ester;CAS_1355197-95-3;Propargyl-PEG6-Boc;4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid, 1,1-dimethylethyl ester;Propargyl-P5-t-butyl ester;PropargylPEG6-tBu ester;Propargyl-PEG5-CH2CH2COOtBu/4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid, 1,1-dimethylethyl ester | | CAS: | 1355197-95-3 | | MF: | C20H36O8 | | MW: | 404.49 | | EINECS: | | | Product Categories: | | | Mol File: | 1355197-95-3.mol |  |
| | Propargyl-PEG6-t-butyl ester Chemical Properties |
| Boiling point | 458.4±40.0 °C(Predicted) | | density | 1.052±0.06 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM |
| | Propargyl-PEG6-t-butyl ester Usage And Synthesis |
| Description | Propargyl-PEG6-t-butyl ester is a heterobifunctional linker consisting of an alkyne group and a t-butyl protected carboxyl group. The alkyne group can participate in copper catalyzed azide-alkyne Click Chemistry to form a stable triazole linkage. The t-butyl group can be hydrolyzed under acidic conditions. | | Uses | Propargyl-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG6-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | PEGs; Alkyl/ether | | References | [1] Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2. |
| | Propargyl-PEG6-t-butyl ester Preparation Products And Raw materials |
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