| Company Name: |
Yichang Zhongyitai Trading Co., Ltd.
|
| Tel: |
0717-6449896 13886658719 |
| Email: |
root@zhongyitai.com |
| Products Intro: |
Product Name:10(11)-Epoxy-Docosapentaenoic acid
CAS:895127-65-8
Purity:98+% Package:100ug
|
| Company Name: |
Alfa Chemistry
|
| Tel: |
1-516-6625404 |
| Email: |
support@alfa-chemistry.com |
| Products Intro: |
Product Name:(4(Z),7Z)-9-[3-(2(Z),5(Z),8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-4,7-nonadienoic acid
CAS:895127-65-8
Purity:95%+ Package:1g;10g;100g;1KG;5KG
|
| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:(±)10(11)-EpDPA
CAS:895127-65-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
(±)10(11)-EpDPA manufacturers
- (±)10(11)-EpDPA
-
- $363.00 / 100μg
-
2024-10-24
- CAS:895127-65-8
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | (±)10(11)-EpDPA Basic information |
| Product Name: | (±)10(11)-EpDPA | | Synonyms: | (±)10(11)-EpDPA;(4(Z),7Z)-9-[3-(2(Z),5(Z),8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-4,7-nonadienoic acid;10(11)-Epoxy-Docosapentaenoic acid;4,7-Nonadienoic acid, 9-[3-(2Z,5Z,8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-, (4Z,7Z)-;10(11)-Epoxy-DPA | | CAS: | 895127-65-8 | | MF: | C22H32O3 | | MW: | 344.49 | | EINECS: | | | Product Categories: | | | Mol File: | 895127-65-8.mol |  |
| | (±)10(11)-EpDPA Chemical Properties |
| Boiling point | 488.8±33.0 °C(Predicted) | | density | 0.994±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 25 mg/mL; DMSO: 20 mg/mL; Ethanol: 50 mg/mL; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL | | pka | 4.58±0.10(Predicted) |
| | (±)10(11)-EpDPA Usage And Synthesis |
| Description | Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid (DHA; ) epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 μM. (±)10(11)-EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in inflammatory and neuropathic pain models and to potently inhibit angiogenesis and tumor growth in in vitro assays. | | Uses | (±)10(11)-EpDPA, a docosahexaenoic acid epoxygenase metabolite, acts as a substrate for soluble epoxide hydrolase (sEH) with a Km value of 5.1 μM for human sEH[1]. | | References | [1] Christophe Morisseau, et al. Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids. J Lipid Res. 2010 Dec;51(12):3481-90. DOI:10.1194/jlr.M006007 |
| | (±)10(11)-EpDPA Preparation Products And Raw materials |
|