Teijin compound 1

Request For Quotation
Teijin compound 1 Suppliers list
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Email: info@efebio.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: QQ：65489617 13301690235
Email: Sales@ATKchemical.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: Shanghai Dongyang Biotechnology Co., Ltd.  
Tel: 0512-13601744364 13601744364
Email: chemsharker@126.com

Teijin compound 1 manufacturers
Teijin compound 1 Basic information
Product Name:Teijin compound 1
Synonyms:CCR2 antagonist 4 hydrochloride;CCR2 antagonist 4 hydrochloride,CCR-2 antagonist 4 hydrochloride;CCR2 antagonist 4 HCl;Teijin compound 1 hydrochloride, CCR2 antagonist
CAS:1313730-14-1
MF:C21H22Cl2F3N3O2
MW:476.32
EINECS:
Product Categories:
Mol File:1313730-14-1.mol
Teijin compound 1 Structure
Teijin compound 1 Chemical Properties
storage temp. Store at -20°C
solubility Soluble to 10 mM in water and to 100 mM in DMSO
form Powder
color White to off-white
Safety Information
MSDS Information
Teijin compound 1 Usage And Synthesis
UsesTeijin Compound 1 is a chemokine receptor, CCR2, inhibitor, which reduces sarcoma cell transendothelial migration and metastasis to the lungs.
in vivo

In ApoE-deficient mice, Vp-TSL targets specifically aortic plaque endothelial VCAM-1 and CCR2 antagonist 4 hydrochloride reduces the mouse monocyte/macrophage cell line (RAW 264.7) adhesion/ infiltration into the aorta[3].

IC 50CCR2b: 180 nM (IC50)
Teijin compound 1 Preparation Products And Raw materials
Tag:Teijin compound 1(1313730-14-1) Related Product Information
4-PiperidinaMine, 1-[3,5-bis(trifluoroMethyl)benzoyl]-2-[(4-chlorophenyl)Methyl]-, (2R,4S)- (9CI) Benzamide, N-[2-oxo-2-[[(3S)-1-(phenylmethyl)-3-pyrrolidinyl]amino]ethyl]-3-(trifluoromethyl)- Benzamide, N-3-piperidinyl-4-(trifluoromethyl)- Teijin compound 1 (2R)-N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-1-methyl-5-oxopyrrolidine-2-carboxamide NA