5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile manufacturers
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| | 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile Basic information |
| Product Name: | 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile | | Synonyms: | 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile;1H-Pyrazole-4-carbonitrile, 5-amino-1-[4-(trifluoromethyl)phenyl]-;5 amino 1 [4 (trifluoromethyl)phenyl] 1H pyrazole 4 carbonitrile,5amino1[4(trifluoromethyl)phenyl]1Hpyrazole4carbonitrile;Xanthine oxidase-IN-14;Xanthine dehydrogenase Inhibitor 1;5-amino-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile, 10 mM in DMSO | | CAS: | 80025-67-8 | | MF: | C11H7F3N4 | | MW: | 252.2 | | EINECS: | | | Product Categories: | | | Mol File: | 80025-67-8.mol |  |
| | 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile Chemical Properties |
| | 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile Usage And Synthesis |
| Uses | Xanthine oxidase-IN-14 (Compound 3f) is an inhibitor for xanthine oxidase, with IC50 >100 μM. Xanthine oxidase-IN-14 inhibits proliferations of cancer cells MCF-7, NCI-H460 and SF-268, with IC50 greater than 150 μM[1]. | | References | [1] Gupta S, et al., Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors. Eur J Med Chem. 2008 Apr;43(4):771-80. DOI:10.1016/j.ejmech.2007.06.002 |
| | 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile Preparation Products And Raw materials |
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