- Licochalcone E
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2023-02-24
- CAS:864232-34-8
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| | Licochalcone E Basic information |
| Product Name: | Licochalcone E | | Synonyms: | Licochalcone E;2-Propen-1-one, 3-[5-[(1S)-1,2-dimethyl-2-propen-1-yl]-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)- | | CAS: | 864232-34-8 | | MF: | C21H22O4 | | MW: | 338.4 | | EINECS: | | | Product Categories: | | | Mol File: | 864232-34-8.mol |  |
| | Licochalcone E Chemical Properties |
| Melting point | 76-80 °C | | Boiling point | 543.745±50.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.172±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | 4°C, protect from light | | solubility | DMSO: 125 mg/mL (369.39 mM) | | form | Solid | | pka | 7.823±0.15(predicted) | | color | Yellow to orange |
| | Licochalcone E Usage And Synthesis |
| Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of Glycyrrhiza uralensis Fisch. | | Uses | Licochalcone E, a flavonoid compound isolated from Glycyrrhiza uralensis, inhibits NF-κB and AP-1 transcriptional activity through the inhibition of AKT and MAPK activation[1]. | | Biological Activity | Licochalcone E, a flavonoid extracted from Glycyrrhiza inflate, inhibits the transcriptional activity of NF-κB and AP-1 by inhibiting the activation of AKT and MAPK. | | target | | | References | [1] Lee HN, et al. Mechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages. Int J Mol Sci. 2013 May 24;14(6):10926-43. DOI:10.3390/ijms140610926 |
| | Licochalcone E Preparation Products And Raw materials |
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