Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]-

Request For Quotation
Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]- Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:IBR2
CAS:313526-24-8
Purity:96.15% Package:5mg;38USD|10mg;68USD|25mg;136USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:IBR2
CAS:313526-24-8
Purity:96.15% Package:5mg;38USD|10mg;68USD|25mg;136USD
Company Name: Aladdin Scientific
Tel:
Email: tp@aladdinsci.com
Products Intro: Product Name:IBR2
CAS:313526-24-8
Purity:98% Package:$80.9/5mg;$140.9/10mg;$520.9/50mg;$910.9/100mg;Bulk package Remarks:98%
Company Name: SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD  
Tel: 13816107857
Email: sales@fortunechem-sh.com
Products Intro: Product Name:IBR2
CAS:313526-24-8
Purity:98% Package:10mg，100mg，500mg，1g，10g
Company Name: Shanghai Raise Chemical Technology Co.,Ltd  
Tel: 15026594951
Email: rs@raise-chem.com
Products Intro: Product Name:Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]-
CAS:313526-24-8
Purity:97% HPLC Package:1g;5g

Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]- manufacturers

  • IBR2
  • IBR2 pictures
  • $64.00
  • 2026-06-02
  • CAS:313526-24-8
  • Purity: 99.50%
  • Supply Ability: 10g
  • IBR2
  • IBR2 pictures
  • $64.00
  • 2026-06-02
  • CAS:313526-24-8
  • Purity: 99.50%
  • Supply Ability: 10g
Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]- Basic information
Product Name:Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]-
Synonyms:Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]-;IBR2;IBR2 (IBR 2);2-(Benzylsulfonyl)-1-(1H-indol-3-yl)-1,2-dihydroisoquinoline;RAD51,Apoptosis,IBR-2,IBR2,inhibit,Inhibitor,IBR 2;2-(Benzylsulfonyl)-1-(1H-indol-3-yl)-1,2-dihydroisoquinoline , IBR2;IBR2, 10 mM in DMSO
CAS:313526-24-8
MF:C24H20N2O2S
MW:400.49
EINECS:
Product Categories:
Mol File:313526-24-8.mol
Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]- Structure
Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]- Chemical Properties
Boiling point 651.2±65.0 °C(Predicted)
density 1.38±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 150 mg/mL (374.54 mM)
form Solid
pka16.67±0.30(Predicted)
color Off-white to pink
Safety Information
MSDS Information
Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]- Usage And Synthesis
UsesIBR2 is a potent and specific RAD51 inhibitor and inhibits RAD51-mediated DNA double-strand break repair. IBR2 disrupts RAD51 multimerization, accelerates proteasome-mediated RAD51 protein degradation, inhibits cancer cell growth and induces apoptosis[1][2].
References[1] Jiewen Zhu, et al. A novel small molecule RAD51 inactivator overcomes imatinib-resistance in chronic myeloid leukaemia. EMBO Mol Med. 2013 Mar;5(3):353-65. DOI:10.1002/emmm.201201760
[2] Zhu J, et al. Synthesis, molecular modeling, and biological evaluation of novel RAD51 inhibitors. Eur J Med Chem. 2015;96:196-208. DOI:10.1016/j.ejmech.2015.04.021
Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]- Preparation Products And Raw materials
Tag:Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]-(313526-24-8) Related Product Information
(E)-1-(1H-indol-3-yl)-2-(styrylsulfonyl)-1,2-dihydroisoquinoline Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]- Isoquinoline, 1,2-dihydro-1-(1H-indol-3-yl)-2-[(phenylmethyl)sulfonyl]-, (1R)-