| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
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| Tel: |
021-50460086-9 15921403865 |
| Email: |
han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:1-((R)-3-(4-amino-3-(4-(phenoxy-d5)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one
Purity:95%HPLC Package:10MG;25MG;50MG;100MG Remarks:DCTI-A-067(Unlabelled:1226872-27-0)
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| Company Name: |
HX Pharmaceutical technology co., LTD
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| Tel: |
15671363360 |
| Email: |
494267389@qq.com |
| Products Intro: |
Product Name:Ibrutinib Impurity 9
CAS:2068022-09-1
Purity:>95%? HPLC Package:10mg；20mg；50mg；100mg
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| Company Name: |
CHINA ISOTOPE CO., LIMITED
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| Tel: |
02151600108 13062666369 |
| Email: |
info@isotopechem.com |
| Products Intro: |
Product Name:Ibrutinib Impurity 3-d5 (PCI-45227-d5)
CAS:2068022-09-1
Purity:1mg Package:1mg Remarks:RMCI04011-1mg
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| Company Name: |
https://www.shachemlin.cn/
|
| Tel: |
68080707 15021879576 |
| Email: |
ming-jiao.wu@chemlin.com.cn |
| Products Intro: |
Product Name:ibrutinib-D5
CAS:2068022-09-1
Purity:97% Package:10g；100g；1kg；3kg；5kg；
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| Company Name: |
Hubei Moco Chemical Co., Ltd.
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| Tel: |
18627753421; 18627756402 |
| Email: |
3001051413@qq.com |
| Products Intro: |
Product Name:N-(1-((S)-1-acryloylpiperidin-3-yl)-
CAS:2068022-09-1
Purity:99%HPLC Package:1mg/1;10mg/1;100mg/1
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| | Ibrutinib Impurity 9 Basic information |
| Product Name: | Ibrutinib Impurity 9 | | Synonyms: | 1-[(3R)-3-[4-amino-3-[4-(2,3,4,5,6-pentadeuteriophenoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2,3-dihydroxypropan-1-one;Ibrutinib Impurity 3-d5;N-(1-((S)-1-acryloylpiperidin-3-yl)-;Ibrutinib Impurity 3-d5 (PCI-45227-d5)(Mixture of Diastereomers);1-((R)-3-(4-Amino-3-(4-(phenoxy-d5)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one;Ibrutinib Impurity 3-d5 (PCI-45227-d5) | | CAS: | 2068022-09-1 | | MF: | C25H21D5N6O4 | | MW: | 479.54254889 | | EINECS: | | | Product Categories: | | | Mol File: | 2068022-09-1.mol |  |
| | Ibrutinib Impurity 9 Chemical Properties |
| | Ibrutinib Impurity 9 Usage And Synthesis |
| Uses | Dihydrodiol-Ibrutinib-d5 is the deuterium labeled Dihydrodiol-Ibrutinib (HY-100659). Dihydrodiol-Ibrutinib is a dihydrodiol active metabolite of Ibrutinib (HY-10997), has inhibitory activity towards BTK approximately 15 times lower than that of ibrutinib[1]. | | References | [1] Sridhar Veeraraghavan,et al. Simultaneous quantification of lenalidomide, ibrutinib and its active metabolite PCI-45227 in rat plasma by LC-MS/MS: application to a pharmacokinetic study. J Pharm Biomed Anal DOI:10.1016/j.jpba.2014.11.041 |
| | Ibrutinib Impurity 9 Preparation Products And Raw materials |
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