| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
|
| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:HUMAN IL-17
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
|
| Company Name: |
Shanghai Kanglang Biotechnology Co., Ltd.
|
| Tel: |
021-61998208 18217752821 |
| Email: |
sales@klbio.cn |
| Products Intro: |
Product Name:Recombinant Human IL-17
Purity:99.99% Package:5μg/646;25μg/1613;100μg/4742;1mg/18967
|
| Company Name: |
Wuhan Chemstan Biotechnology Co., Ltd.
|
| Tel: |
027-65317797 15926423062 |
| Email: |
422450190@qq.com |
| Products Intro: |
Product Name:Recombinant Human IL17/IL17A Protein, No Tag
Purity:>90% as determined by SDS-PAGE Package:50μg, 100μg
|
|
| Product Name: | HUMAN IL-17 | | Synonyms: | RECOMBINANT HUMAN IL-17;Anti-IL17A antibody produced in goat;Mouse Interleukin 17A elisa kit;INTERLEUKIN-17, HUMAN;HUMAN IL-17;HUMAN CTLA-8;IL-17, HUMAN;HUMAN IL-17A/17A | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![HUMAN IL-17 Structure]() |
| | HUMAN IL-17 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | color | off-white to yellow | | biological source | human |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | HUMAN IL-17 Usage And Synthesis |
| Uses | The gene IL17A (interleukin 17A), also referred to as IL-17, is mapped to human chromosome 6p12.2. The gene contain three exons and encodes a proinflammatory cytokine produced by activated T cells. | | Biological Activity | The cytokine interleukin 17A is involved in the activation of proinflammatory cytokines, chemokines, and cell adhesion molecules in several cell types such as, macrophages, dendritic cells, T cells, synovial cells, and endothelial cells. Overexpression of this protein has been associated with rheumatoid arthritis, systemic lupus erythematosus, Behcet′s disease, allograft rejection, nephritic syndrome, asthma, and multiple sclerosis. In mice, it has been observed to be implicated in the development of allergic and autoimmune diseases. Polymorphism in IL17A gene has been associated with lung cancer. | | Description | Interleukin-17A Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain containing a total of 264 amino acids (2 chains of 132 aa) and having a molecular mass of 31kDa.
The IL-17 is purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |
| | HUMAN IL-17 Preparation Products And Raw materials |
|