| Company Name: |
BOC Sciences |
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
- AB-423
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- $35.00
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2026-07-17
- CAS:1572510-80-5
- Purity: 99.89%
- Supply Ability: 10g
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| Product Name: | AB-423 | | Synonyms: | AB-423;CS-2686;AB423;AB-423;AB 423;Benzamide, N-(3,4-difluorophenyl)-2-fluoro-5-[[[(1R)-1-methylpropyl]amino]sulfonyl]-;N-(3,4-Difluorophenyl)-2-fluoro-5-[[[(1R)-1-methylpropyl]amino]sulfonyl]benzamide;AB 423,HBV,AB423,inhibit,Hepatitis B virus,AB-423,Inhibitor;AB-423, 10 mM in DMSO;AB-423 (AB423 | | CAS: | 1572510-80-5 | | MF: | C17H17F3N2O3S | | MW: | 386.39 | | EINECS: | | | Product Categories: | | | Mol File: | 1572510-80-5.mol |  |
| | AB-423 Chemical Properties |
| density | 1.372±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:88.5(Max Conc. mg/mL);229.04(Max Conc. mM)
Ethanol:77.0(Max Conc. mg/mL);199.28(Max Conc. mM) | | form | Solid | | pka | 10.84±0.70(Predicted) | | color | White to off-white | | CAS DataBase Reference | 1572510-80-5 |
| | AB-423 Usage And Synthesis |
| Uses | N-(3,4-Difluorophenyl)-2-fluoro-5-[[[(1R)-1-methylpropyl]amino]sulfonyl]benzamide, is an inhibitor of HBV capsid assembly. AB-423 shows inhibitory effect on rcDNA production in AML12-HBV10 and HepDE19 cells with EC50s of ～0.260 μM | | in vivo | AB-423 (30 and 100 mg/kg, p.o. bid) blocks HBV replication in a mouse model of HBV. AB-423 (100 mg/kg, p.o. bid) with entecavir (ETV, 100 ng/mg, qd, p.o.) or 0.1 mg/kg dose of ARB-1467 potently inhibits serum HBV DNA in an HDI model of HBV in immunodeficient NOD-SCID mice[1]. |
| | AB-423 Preparation Products And Raw materials |
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