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| | Ethyl 3-chlorobenzoylformate Basic information |
| Product Name: | Ethyl 3-chlorobenzoylformate | | Synonyms: | (3-CHLOROPHENYL)GLYOXYLIC ACID ETHYL ESTER;(3-Chlorophenyl)oxoacetic acid ethyl ester;3-Chloro-oxo-benzeneacetic acid ethyl ester;Benzeneacetic acid,3-chloro-a-oxo-, ethyl ester;Benzeneacetic acid, 3-chloro-α-oxo-, ethyl ester;Ethyl 2-(3-chlorophenyl)-2-oxoacetate;Ethyl 3-chlorobenzoylformate | | CAS: | 62123-73-3 | | MF: | C10H9ClO3 | | MW: | 212.63 | | EINECS: | | | Product Categories: | Aromatic Esters | | Mol File: | 62123-73-3.mol |  |
| | Ethyl 3-chlorobenzoylformate Chemical Properties |
| Boiling point | 88°C 0,1mm | | density | 1.2270 g/cm3 | | storage temp. | Sealed in dry,Room Temperature | | Appearance | pale yellow liquid | | CAS DataBase Reference | 62123-73-3(CAS DataBase Reference) |
| | Ethyl 3-chlorobenzoylformate Usage And Synthesis |
| Synthesis | GENERAL METHODS: 3-Chlorobenzoylacetonitrile (1.0 mmol) and PIDA (2.2 mmol) were dissolved in ethanol (8 mL), and the reaction was stirred under reflux conditions for 0.5 hours. The reaction process was monitored by thin layer chromatography (TLC). After completion of the reaction, the reaction mixture was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent ratio 20:1 petroleum ether/ethyl acetate) to afford the target product ethyl 3-chlorobenzoylformate. Note: The solvent used in this synthesis step is methanol (MeOH). | | References | [1] Tetrahedron Letters, 2015, vol. 56, # 24, p. 3793 - 3795 |
| | Ethyl 3-chlorobenzoylformate Preparation Products And Raw materials |
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