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| | DL-CATECHIN Basic information |
| Product Name: | DL-CATECHIN | | Synonyms: | TRANS-1,2,4,5-BENZENETETRACARBOXYLIC ACID;TRANS-2-(3,4-DIHYDROXYPHENYL)3,4-DIHYDRO-2H-1-BENZOPYRAN-3,5,7-TRIOL;TRANS-PYROMELLITIC ACID;DL-CATECHIN;DL-CATECHIN CATECHINS;(-)-CYANIDANOL-3;CATECHIN, DL-;CATECHIN | | CAS: | 88191-48-4 | | MF: | C15H16O7 | | MW: | 308.29 | | EINECS: | | | Product Categories: | | | Mol File: | 88191-48-4.mol |  |
| | DL-CATECHIN Chemical Properties |
| | DL-CATECHIN Usage And Synthesis |
| Uses | Catechin hydrate inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. | | Definition | ChEBI: The monohydrate of (+)-catechin. | | in vivo | Animals treated with Catechin at the lowest tested dose, i.e., 50 mg/kg, p.o. have spent comparatively more time in exploring the novel object in the choice trial, however, the difference is not statistically significant. Catechin prevents the time-induced episodic memory deficits in a dose-dependent manner, the most effective being 200 mg/kg, p.o.. Treatment with Catechin prevents the rise in MPO level compare to DOX alone treatment group (21.98±9.44 and 36.76±4.39% in the hippocampus and the frontal cortex respectively)[3]. | | IC 50 | COX-1: 1.4 μM (IC50) | | References | [1] Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40(2):173-9. DOI:10.1207/S15327914NC402_14
[2] Alshatwi AA. Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. J Exp Clin Cancer Res. 2010 Dec 17;29:167. DOI:10.1186/1756-9966-29-167
[3] Cheruku SP, et al. Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats. Cytotechnology. 2018 Feb;70(1):245-259. DOI:10.1007/s10616-017-0138-8 |
| | DL-CATECHIN Preparation Products And Raw materials |
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