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(-)-CATECHIN

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(-)-CATECHIN manufacturers

  • (-)-CATECHIN HYDRATE
  • (-)-CATECHIN HYDRATE  pictures
  • $1.10
  • 2026-08-20
  • CAS:18829-70-4
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons Min
  • (-)-Catechin
  • (-)-Catechin pictures
  • $40.00
  • 2026-07-14
  • CAS:18829-70-4
  • Purity: 98.74%
  • Supply Ability: 10g
(-)-CATECHIN Basic information
Preparation
Product Name:(-)-CATECHIN
Synonyms:(+)-TRANS-3,3',4',5,7-PENTAHYDROXYFLAVANE;(-)-CATECHIN HYDRATE;(L)-CATECHIN HYDRATE;3,5,7,3',4'-PENTAHYDROXYFLAVANE HYDRATE;(2S,3R)-2-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-1(2H)-BENZOPYRAN-3,5,7-TRIOL;(2S-trans)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol;(2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-pyran-3,5,7-triol, 3,3,4,5,7-Pentahydroxyflavan, (-)-Cyanidanol-3;(2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol, (-)-trans-3,3μ,4μ,5,7-Pentahydroxyflavane
CAS:18829-70-4
MF:C15H14O6
MW:290.27
EINECS:242-611-7
Product Categories:Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;john's
Mol File:18829-70-4.mol
(-)-CATECHIN Structure
(-)-CATECHIN Chemical Properties
Melting point 93-96°; 175-177° when anhydr
alpha D -16.8°
Boiling point 630.4±55.0 °C(Predicted)
density 1.593±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 25 mg/ml; DMSO: 15 mg/ml; Ethanol: 5 mg/ml; PBS (pH 7.2): 1 mg/ml
form A crystalline solid
pka9.54±0.10(Predicted)
color White to off-white
biological sourcegreen tea
InChIInChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m1/s1
InChIKeyPFTAWBLQPZVEMU-HIFRSBDPSA-N
SMILES[C@@H]1(C2=CC=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C[C@H]1O
LogP0.490 (est)
CAS DataBase Reference18829-70-4(CAS DataBase Reference)
Safety Information
WGK Germany 3
10
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
(-)-CATECHIN Usage And Synthesis
PreparationCatechins, possessing a 2-phenylbenzodihydropyran structure, belong to the flavanol class of compounds. The biosynthesis of catechins in tea plants mainly consists of four parts: the shikimic acid pathway, the phenylpropane pathway, the synthesis of non-ester catechins, and the synthesis of ester catechins. In the shikimic acid pathway, erythrose 4-phosphate (E4P) produced by the pentose phosphate pathway and phosphoenolpyruvate (PEP) produced by the glycolysis pathway are synthesized into 3-deoxy-D-7-phosphoarabinoheptanulose synthase (DAHPS) to produce 3-deoxy-D-7-phosphoarabinoheptanulose acid (DHAP). Subsequently, under the action of other enzymes, a series of reactions yield aryl amino acids, vitamins, lignin, phenolic substances, alkaloids, and other products. Among these, phenylalanine, under the action of phenylalanine ammonia-lyase (PAL), enters the phenylpropane pathway to synthesize p-coumaroyl-CoA. One molecule of coumaroyl-CoA and three molecules of malonyl-CoA synthesize naringenin chalcone under the action of chalcone synthase (CHS), and then cyclize under the action of chalcone isomerase (CHI) to give naringenin. Chalcone is an important precursor for the synthesis of compounds such as catechins and anthocyanins, and is the basic molecular skeleton of catechin compounds. This O1 and C2 linkage to form a pyran ring provides important information for the chemical synthesis of catechins. Naringenin introduces one and two hydroxyl groups into the B ring under the action of flavonoid 3'-hydroxylase (F3'H) and flavonoid 3',5'-hydroxylase (5'H) to give flavanones, which are then reduced by flavanone 3-hydroxylase (F3H) and dihydroflavanol 4-reductase (DFR) to synthesize colorless anthocyanins. Colorless anthocyanins can be directly reduced by reductase (LAR) to non-phenotypic catechins, namely catechins and GC, or can be continuously catalyzed by anthocyanin synthase (ANS) and anthocyanin reductase (ANR) to produce phenotypic catechins EC and EGC; isotope labeling experiments have found that there may also be an interconversion mechanism between EC and EGC.
Uses(-)-Catechin has been used:
  • to test its binding affinity towards estrogen receptor
  • as a reference standard in high-performance liquid chromatography for quantification of polyphenols from plant extracts (HPLC)
  • as a reference standard in kinetic studies to quantify antioxidants from Iranian green tea leaves

UsesA natural phenol antioxidant plant secondary metabolite.
UsesIn dyeing and tanning.
DefinitionChEBI: (-)-catechin is the (-)-enantiomer of catechin. It has a role as a metabolite. It is an enantiomer of a (+)-catechin.
General DescriptionThis substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol ActionsCatechins have wide biological functionality. They induce antiviral and anticancer activities. Catechins also play a key role in regulating carbohydrate and lipid metabolism. It prevents fat accumulation.
(-)-CATECHIN Preparation Products And Raw materials
Tag:(-)-CATECHIN(18829-70-4) Related Product Information
Cesium hydroxide Quercetin dihydrate YTTRIUM CHLORIDE HEXAHYDRATE Ruthenium(III) chloride hydrate (+)-CATECHIN HYDRATE (±)-Catechin DL-CATECHIN (+/-)-CATECHIN HYDRATE,CATECHIN HYDRATE (-)-GALLOCATECHIN PROCYANIDIN A2 (-)-CATECHIN HYDRATE (-)-CATECHIN GALLATE (-)-Gallocatechin gallate