(R)-PK11195

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(R)-PK11195 Suppliers list
Company Name: Shanghai Han-Xiang Chemical Co., Ltd.  
Tel: 17754423994
Email: candy@biochempartner.com
(R)-PK11195 Basic information
Product Name:(R)-PK11195
Synonyms:RP 52028;(R)-PK11195;PK 11195;1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-ISOQUINOLINE-3-CARBOXAMIDE-(R);3-ISOQUINOLINECARBOXAMIDE, 1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-, (R)
CAS:85340-56-3
MF:C21H21ClN2O
MW:352.86
EINECS:
Product Categories:
Mol File:85340-56-3.mol
(R)-PK11195 Structure
(R)-PK11195 Chemical Properties
CAS DataBase Reference85340-56-3
Safety Information
MSDS Information
(R)-PK11195 Usage And Synthesis
Chemical PropertiesYellowish oil
UsesPK 11195 is a high affinity peripheral benzodiazepine receptor (PBR) ligand. PK 11195 has been shown to regulate protein phosphorylation in rat brain mitochondria under control of Ca2+. PK11195 promotes mitochondrial apoptosis and blocks P-glycoprotein (Pgp)-mediated drug efflux to chemosensitize cancer cells.
DefinitionChEBI: PK-11195 is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine It has a role as an antineoplastic agent. It is a member of isoquinolines, a monocarboxylic acid amide, an aromatic amide and a member of monochlorobenzenes.
(R)-PK11195 Preparation Products And Raw materials
Tag:(R)-PK11195(85340-56-3) Related Product Information
1-(2-Chlorophenyl)-N-(1-methylpropyl)-isoquinoline-3-carboxamide 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide 2-Pyridinecarboxamide,6-methyl-(9CI) (R)-PK11195 3-isoquinolinecarboxaldehyde 6-(4-fluorophenyl)pyridine-2-carbaldehyde