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Spirodiclofen

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CAS:148477-71-8
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Products Intro: Product Name:Spirodiclofen
CAS:148477-71-8
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Spirodiclofen manufacturers

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  • 2026-07-01
  • CAS:148477-71-8
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  • CAS:148477-71-8
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Spirodiclofen Basic information
Product Name:Spirodiclofen
Synonyms:SPIRODICLOFEN;3-(2,4-DICHLOROPHENYL)-2-OXO-1-OXASPIRO[4.5]DEC-3-EN-4-YL) 2,2-DIMETHYLBUTYRATE;Spirodiclofen, Pestanal;SPIRODICLOFEN 10 NG/UL PESTANAL;baj2740;spirodiclofen(bsi, pa iso);[3-(2,4-Dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl] 2,2-dimethylbutanoate;Daniemon(TM)
CAS:148477-71-8
MF:C21H24Cl2O4
MW:411.32
EINECS:604-636-5
Product Categories:Agrochemical;Pesticide intermediates
Mol File:148477-71-8.mol
Spirodiclofen Structure
Spirodiclofen Chemical Properties
Melting point 101-108°
Boiling point 550.2±50.0 °C(Predicted)
density 1.28±0.1 g/cm3(Predicted)
vapor pressure 0-0Pa at 20-25℃
Fp 4 °C
storage temp. 0-6°C
solubility Chloroform (Slightly), DMSO, Methanol (Sparingly)
form Solid
color White to Off-White
Henry's Law Constant1.7×102 mol/(m3Pa) at 25℃, HSDB (2015)
Major Applicationagriculture
environmental
InChI1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(14-9-8-13(22)12-15(14)23)18(24)27-21(17)10-6-5-7-11-21/h8-9,12H,4-7,10-11H2,1-3H3
InChIKeyDTDSAWVUFPGDMX-UHFFFAOYSA-N
SMILESCCC(C)(C)C(=O)OC1=C(C(=O)OC12CCCCC2)c3ccc(Cl)cc3Cl
LogP5.83 at 20℃ and pH4
EPA Substance Registry SystemSpirodiclofen (148477-71-8)
Safety Information
Hazard Codes Xi,Xn,F
Risk Statements 43-67-65-63-48/20-38-11
Safety Statements 36/37-62
RIDADR UN1294 3/PG 2
WGK Germany 2
Storage Class6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard ClassificationsAquatic Chronic 1
Carc. 1B
Repr. 2
Skin Sens. 1B
STOT RE 2
Hazardous Substances Data148477-71-8(Hazardous Substances Data)
ToxicityLD50 in rats (mg/kg): >2500 orally; >2000 dermally (24 hr); LC50 (4 hr) in rats (mg/m3): >5000 by inhalation; LC50 (96 hr) in fish: >68 mg/l (Wachendorff)
MSDS Information
Spirodiclofen Usage And Synthesis
DescriptionSpirodiclofen is a new selective, non systemic acaricide belonging to the chemical group of the spirocyclic tetronic acid derivatives. It acts by interfering with mite development, thereby controlling such pests as Panonychus spp., Phyllocoptruta spp., Brevipalpus spp., and Aculus and Tetranychus species. Spirodiclofen is active by contact to mite eggs, all nymphal stages, and adult females (adult males are not effected). Spirodiclofen is structurally similar to spiromesifen, which is also a tetronic acid insecticide. Spirodiclofen is registered worldwide for use on a variety of crops including citrus, pome fruits, stone fruits, grapes and ornamentals.
UsesSpirodiclofen is a tetronic acid acaricide fungicide used in controlling red mites. Spirodiclofen is used in cannabis testing kits as a component of pesticide mixes (P698240).
DefinitionChEBI: Spirodiclofen is an organochlorine acaricide, a dichlorobenzene, an oxaspiro compound and a gamma-lactone. It derives from a 1,3-dichlorobenzene.
SynthesisSpirodiclofen is commercially produced via a multi-step synthesis starting with the condensation of 2,2-dimethyl-1,3-dioxane-4,6-dione (Meldrum’s acid) with 3-(2,4-dichlorophenyl)propanoyl chloride under basic conditions to form an intermediate enol ester, which undergoes thermal cyclisation in the presence of 1,1,1-trichloroethane or similar solvent to yield the spirocyclic core; subsequent esterification with 2,2-dimethylbutyryl chloride and purification give the active compound.
Mode of actionSpirodiclofen is a progenitor of tetronic acid derivates (inhibitors of acetyl CoA carboxylase), characterized by an original (unique) mechanism of action which combines long-lasting protection with anthocorid safety for effective integrated pest management.
It interferes/inhibits the lipid biosynthesis of Mites, Mealybugs and Pear-psylla.
Pesticide TypeAcaricide; Insecticide
Spirodiclofen Preparation Products And Raw materials
Tag:Spirodiclofen(148477-71-8) Related Product Information
Phenylphosphonic dichloride Pyridaben 16-Denyprasterone acetate 4-Phenylbutyric acid N,N-Dimethylallylamine Dichlorodimethylsilane Hexythiazox Fenpyroximate 4-Aminobutyric acid Chlorodimethylphenylsilane 3-(2,4-Dichlorophenyl)-4-hydroxy-1-oxaspiro(4,5)dec-3-en-2-one Spirodiclofen Impurity 2 Spirodiclofen Impurity 3 tert-Butyl 4-[[[(E)-[(1,3-Dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino]oxy]methyl]benzoate Carfentrazone-ethyl Vinyl pivalate ETHYL 2,4-DICHLOROPHENYL ACETATE Ethyl 2-phenylacrylate