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| | S(+)-3 4-mdma HCl Basic information |
| | S(+)-3 4-mdma HCl Chemical Properties |
| Melting point | 147-148° (Bailey); mp 152-153° (Braun) | | Fp | 11°C | | storage temp. | 2-8°C | | solubility | H2O: soluble | | form | solid | | color | white | | Optical Rotation | [α]24/D +18.38°, c = 1 in H2O(lit.) |
| | S(+)-3 4-mdma HCl Usage And Synthesis |
| Description | 3,4-MDMA (hydrochloride) (CRM) (Item No. ISO60190) is a certified reference material that is structurally categorized as an amphetamine. Also known as ecstasy, it is a euphoric entactogen that is illegal in most countries and is regulated (Schedule I) in the United States. It inhibits transporters for noradrenaline and serotonin (IC50s = 6.6 and 34.8 μM, respectively) and blocks the uptake of dopamine (IC50 = 0.48 μM). This neurotoxic compound, unlike typical amphetamines, suppresses locomotor activity in animals at both low and high doses. This product is intended for research and forensic applications. | | Chemical Properties | Off-White to Pale Pink Solid | | Uses | Entactogen; N-methyl derivative of MDA. (S)-Form possesses more potent CNS activity.
Controlled substance (hallucinogen). | | Uses | 3,4-Methylenedioxymethamphetamine (MDMA) is an Entactogen; It is the N-methyl derivative of MDA. The (S)-form of MDMA possesses more potent CNS activity than the (R) form of MDMA.
MDMA is controlled substance (hallucinogen). | | References | [1] DAVID MICHAEL WOOD. Variability in the 3,4-methylenedioxymethamphetamine content of “ecstasy” tablets in the UK.[J]. Emergency Medicine Journal, 2011, 28 9: 764-765. DOI: 10.1136/emj.2010.092270 [2] PATIL ARMENIAN. Multiple MDMA (Ecstasy) overdoses at a rave event: a case series.[J]. Journal of Intensive Care Medicine, 2013, 28 4: 252-258. DOI: 10.1177/0885066612445982 [3] MATEUSZ KACPER WONIAK . Application of gas chromatography–tandem mass spectrometry for the determination of amphetamine-type stimulants in blood and urine[J]. Journal of pharmaceutical and biomedical analysis, 2018, 148: Pages 58-64. DOI: 10.1016/j.jpba.2017.09.020 |
| | S(+)-3 4-mdma HCl Preparation Products And Raw materials |
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