| Company Name: |
BOC Sciences |
| Tel: |
16314854226; +8616314854226 |
| Email: |
inquiry@bocsci.com |
cRIPGBM manufacturers
- cRIPGBM
-
- $3520.00
-
2026-07-27
- CAS:2361988-76-1
- Purity:
- Supply Ability: 10g
|
| | cRIPGBM Basic information |
| | cRIPGBM Chemical Properties |
| | cRIPGBM Usage And Synthesis |
| Uses | cRIPGBM, a proapoptotic derivative of RIPGBM, a cell type-selective inducer of apoptosis in GBM cancer stem cells (CSCs) by binding to receptor-interacting protein kinase 2 (RIPK2), with an EC50 of 68 nM in GBM-1 cells[1]. | | IC 50 | RIPK2; Caspase-1 | | References | [1] Lucki NC, et al. A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6435-6440. DOI:10.1073/pnas.1816626116 |
| | cRIPGBM Preparation Products And Raw materials |
|