(S,S)-2-[3-(5-amino-1-carboxy-pentyl)-ureido]-pentanedioic acid

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(S,S)-2-[3-(5-amino-1-carboxy-pentyl)-ureido]-pentanedioic acid manufacturers
(S,S)-2-[3-(5-amino-1-carboxy-pentyl)-ureido]-pentanedioic acid Basic information
Product Name:(S,S)-2-[3-(5-amino-1-carboxy-pentyl)-ureido]-pentanedioic acid
Synonyms:(S,S)-2-[3-(5-amino-1-carboxy-pentyl)-ureido]-pentanedioic acid;L-Glutamic acid, N-[[[(1S)-5-amino-1-carboxypentyl]amino]carbonyl]-;(S)?-?2-?(3-?((S)?-?5-?amino-?1-?carboxypentyl)?ureido)?pentanedioic acid;GCPII-IN-1;Lys-Urea-Glu
CAS:1025796-32-0
MF:C12H21N3O7
MW:319.31
EINECS:
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Mol File:1025796-32-0.mol
(S,S)-2-[3-(5-amino-1-carboxy-pentyl)-ureido]-pentanedioic acid Structure
(S,S)-2-[3-(5-amino-1-carboxy-pentyl)-ureido]-pentanedioic acid Chemical Properties
Boiling point 682.1±55.0 °C(Predicted)
density 1.390±0.06 g/cm3(Predicted)
pka3.76±0.10(Predicted)
form Solid
color White to off-white
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MSDS Information
(S,S)-2-[3-(5-amino-1-carboxy-pentyl)-ureido]-pentanedioic acid Usage And Synthesis
DescriptionGCPII-IN-1 is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor.
UsesGCPII-IN-1 is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM[1].
References[1] Jan Tykvart, et al. Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg Med Chem. 2014 Aug 1;22(15):4099-108. DOI:10.1016/j.bmc.2014.05.061
(S,S)-2-[3-(5-amino-1-carboxy-pentyl)-ureido]-pentanedioic acid Preparation Products And Raw materials
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