Glu-Urea-Lys(Ahx-HYNIC)

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Glu-Urea-Lys(Ahx-HYNIC) Basic information
Product Name:Glu-Urea-Lys(Ahx-HYNIC)
Synonyms:Glu-Urea-Lys(Ahx-HYNIC);(14S,18S)-1-(6-Hydrazineylpyridin-3-yl)-1,8,16-trioxo-2,9,15,17-tetraazaicosane-14,18,20-tricarboxylic acid;Retatrutide Intermediate
CAS:2213408-17-2
MF:C24H37N7O9
MW:567.59
EINECS:
Product Categories:
Mol File:2213408-17-2.mol
Glu-Urea-Lys(Ahx-HYNIC) Structure
Glu-Urea-Lys(Ahx-HYNIC) Chemical Properties
density 1.45±0.1 g/cm3(Predicted)
pka3.78±0.10(Predicted)
form Solid
color White to off-white
SequenceGlu-Urea-Lys(Ahx-HYNIC)
Safety Information
MSDS Information
Glu-Urea-Lys(Ahx-HYNIC) Usage And Synthesis
UsesHYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as 188Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research[1]. HYNIC-PSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
References[1] Hadisi M, et al. Preclinical evaluation of 188 Re-HYNIC-PSMA as a novel therapeutic agent[J]. Journal of Radioanalytical and Nuclear Chemistry, 2022, 331(2): 841-849.
Glu-Urea-Lys(Ahx-HYNIC) Preparation Products And Raw materials
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