| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
|
| Tel: |
021-50460086-9 15921403865 |
| Email: |
han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:Remdesivir
Phosphate Impurity
CAS:1911578-74-9
Purity:95%HPLC Package:10MG;25MG;50MG;100MG Remarks:DCTI-C-977
|
| Company Name: |
AF Biochem Co., Ltd.
|
| Tel: |
+86-028-60911900 13540204019 |
| Email: |
sales@afbiochem.com |
| Products Intro: |
Product Name:--
CAS:1911578-74-9
Purity:HPLC 98% Package:1g; 10g; 1kg; 25kg
|
Remdesivir impurity manufacturers
|
| | Remdesivir impurity Basic information |
| Product Name: | Remdesivir impurity | | Synonyms: | Remdesivir Impurity 40;Remdesivir nucleoside monophosphate;Remdesivir impurity;D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-, 6-(dihydrogen phosphate);Remdesivir Impurity 46;Remdesivir Nucleoside Monophosphate Ammonium salt;Remdesivir Phosphate ImpurityQ: What is
Remdesivir Phosphate Impurity Q: What is the CAS Number of
Remdesivir Phosphate Impurity;Remdesivir Impurity 29（Remdesivir nucleoside monophosphate） | | CAS: | 1911578-74-9 | | MF: | C12H14N5O7P | | MW: | 371.25 | | EINECS: | | | Product Categories: | | | Mol File: | 1911578-74-9.mol |  |
| | Remdesivir impurity Chemical Properties |
| density | 2.07±0.1 g/cm3(Predicted) | | pka | 1.86±0.10(Predicted) | | form | Solid | | color | White to off-white |
| | Remdesivir impurity Usage And Synthesis |
| Uses | Remdesivir nucleoside monophosphate is a metabolite of Remdesivir[1]. Remdesivir is a nucleoside analogue with effective antiviral activity against SARS-CoV and MERS-CoV[2]. | | Definition | ChEBI: GS-441524 monophosphate is a C-nucleoside phosphate that is GS-441524 in which the 5'-hydroxy group has been replaced by a phosphate group. In cells, GS-441524 monophosphate gets converted into the pharmacologically active triphosphate form (GS-443902). It has a role as an anticoronaviral agent, an antiviral drug and a drug metabolite. It is a C-nucleoside phosphate, an aromatic amine, a nitrile and a pyrrolotriazine. It is functionally related to a GS-441524. | | References | [1] Byoung Kwon Chun, et al. or treating filoviridae virus infections. US20160122374.
[2] Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18. DOI:10.1128/mBio.00221-18 |
| | Remdesivir impurity Preparation Products And Raw materials |
|