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5,8-Quinolinequinone manufacturers
- 5,8-QUINOLINEQUINONE
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- $9.80
-
2020-01-05
- CAS:10470-83-4
- Min. Order: 1KG
- Purity: 97%-99%
- Supply Ability: 1kg -1000kg
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| | 5,8-Quinolinequinone Basic information |
| Product Name: | 5,8-Quinolinequinone | | Synonyms: | 5,8-Qinolinequinone;5,8-Dihydroquinoline-5,8-dione;5,8-Quinolinedione;Aids000101;Aids-000101;5,8-Dihydro-5,8-dioxoquinoline;DA 276;NSC 682996 | | CAS: | 10470-83-4 | | MF: | C9H5NO2 | | MW: | 159.14 | | EINECS: | | | Product Categories: | | | Mol File: | 10470-83-4.mol |  |
| | 5,8-Quinolinequinone Chemical Properties |
| Melting point | 129℃ (DEC.) | | Boiling point | 333.6±42.0 °C(Predicted) | | density | 1.374 | | storage temp. | Inert atmosphere,Room Temperature | | pka | -0.71±0.20(Predicted) |
| | 5,8-Quinolinequinone Usage And Synthesis |
| Synthesis Reference(s) | Tetrahedron Letters, 31, p. 4871, 1990 DOI: 10.1016/S0040-4039(00)97755-4 | | Synthesis | Iodobenzene diacetate (10.35 mmol, 3.3 g) was dissolved in 12 mL of a solvent mixture of acetonitrile and water (2:1, v/v) under nitrogen atmosphere and cooled to 0°C. To this solution was added quinolin-5-ol (3.45 mmol, 0.50 g) and the reaction was stirred at this temperature for 1 hour. Upon completion of the reaction, 40 mL of water was added to dilute the reaction mixture, followed by extraction with ethyl acetate (3 x 20 mL). The organic phases were combined, washed with saturated saline, dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford the target product 5,8-quinoline quinone (4) as a yellow solid in 82% yield. Mass spectrum (ESI) m/z = 160 [M + H]+. | | References | [1] Tetrahedron Letters, 1990, vol. 31, # 34, p. 4871 - 4872
[2] Organic and Biomolecular Chemistry, 2011, vol. 9, # 13, p. 4959 - 4976
[3] European Journal of Medicinal Chemistry, 2018, vol. 154, p. 199 - 209
[4] Synthetic Communications, 1999, vol. 29, # 18, p. 3063 - 3066 |
| | 5,8-Quinolinequinone Preparation Products And Raw materials |
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