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Methyl 2,5-dihydroxycinnamate

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Methyl 2,5-dihydroxycinnamate manufacturers

Methyl 2,5-dihydroxycinnamate Basic information
Product Name:Methyl 2,5-dihydroxycinnamate
Synonyms:2,5-DIHYDROXYMETHYLCINNAMATE;2,5-DIHYDROXYCINNAMIC ACID METHYL ESTER;ERBSTATIN ANALOG;ERBSTATIN ANALOGUE;3-(2,5-Dihydroxy-phenyl)-acrylicacidmethylester;Erbstatin analog, Methyl 2,5-dihydroxycinnamate;Methyl 2,5-dihyroxycinnamate;2,5-Dihydroxycinnamic acid methyl ester,Erbstatin analog, Methyl 2,5-dihydroxycinnamate
CAS:63177-57-1
MF:C10H10O4
MW:194.18
EINECS:
Product Categories:Aromatic Cinnamic Acids, Esters and Derivatives;All Inhibitors;Inhibitors;Tyrosine Kinase Inhibitors
Mol File:63177-57-1.mol
Methyl 2,5-dihydroxycinnamate Structure
Methyl 2,5-dihydroxycinnamate Chemical Properties
Melting point 178-180°C
Boiling point 400.735±35.00 °C(Press: 760.00 Torr)(predicted)
density 1.318±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility 0.1 M NaOH: soluble
form crystalline
pka9.139±0.43(predicted)
color yellow
Water Solubility Soluble in methanol or 0.1M NaOH. Insoluble in water
CAS DataBase Reference63177-57-1(CAS DataBase Reference)
Safety Information
Hazard Codes T
Risk Statements 23/24/25-36/37/38
Safety Statements 22-26-36-45
WGK Germany 3
HS Code 2918.29.7500
HazardClass 6.1
MSDS Information
ProviderLanguage
SigmaAldrich English
Methyl 2,5-dihydroxycinnamate Usage And Synthesis
Chemical PropertiesYellow-Brown Crystalline Powder
UsesAn inhibitor of the EGF receptor associated tyrosine kinase
UsesA stable Erbstatin analogue that inhibits tyrosine kinase. Shown to delay the S-phase induction by epidermal growth factor in quiescent normal rat kidney cells, without affecting the total amount of DNA synthesis
DefinitionChEBI: 2,5-dihydroxycinnamic acid methyl ester is a cinnamate ester that is the methyl ester of 2,5-dihydroxycinnamic acid. It has a role as a human urinary metabolite, a plant metabolite, a geroprotector and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a cinnamate ester, a member of hydroquinones and a methyl ester.
Methyl 2,5-dihydroxycinnamate Preparation Products And Raw materials
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