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| | 4-Bromo-2-fluorobenzaldehyde dimethyl acetal Basic information |
| | 4-Bromo-2-fluorobenzaldehyde dimethyl acetal Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | Appearance | Light yellow to yellow Liquid |
| Hazard Codes | Xi | | HS Code | 2913000090 |
| | 4-Bromo-2-fluorobenzaldehyde dimethyl acetal Usage And Synthesis |
| Synthesis | Step 1: Synthesis of 4-bromo-1-(dimethoxymethyl)-2-fluorobenzene
4-Bromo-2-fluorobenzaldehyde (5 g, 24.6 mmol) was dissolved in 2 M methanol hydrochloric acid solution (100 mL) and stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction solution was concentrated and dried under reduced pressure to afford the title compound 4-bromo-1-(dimethoxymethyl)-2-fluorobenzene (6.1 g, 99% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.52-7.39 (m, 1H), 7.33-7.27 (m, 1H), 7.27-7.20 (m, 1H), 5.54 (s, 1H), 3.36 (s, 6H). | | References | [1] Patent: WO2013/92941, 2013, A1. Location in patent: Page/Page column 39
[2] Patent: US2006/58361, 2006, A1. Location in patent: Page/Page column 32 |
| | 4-Bromo-2-fluorobenzaldehyde dimethyl acetal Preparation Products And Raw materials |
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