4-Chlorophenylguanidine hydrochloride manufacturers
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| | 4-Chlorophenylguanidine hydrochloride Basic information |
| Product Name: | 4-Chlorophenylguanidine hydrochloride | | Synonyms: | 4-ChlorophenylguanidineHCl;p-Chlorophenylguanidine Hydrochloride;Chlorhexidine Digluconate EP Impurity E;(4-Chlorophenyl)guanidine Hydrochlo;1-(4-chlorophenyl)guanidine hydrochloride;BW 65-100 (hydrochloride);Chlorhexidine Diacetate Impurity E as Hydrochloride;Chlorhexidine Diacetate EP Impurity E as Hydrochloride | | CAS: | 14279-91-5 | | MF: | C7H9Cl2N3 | | MW: | 206.07 | | EINECS: | | | Product Categories: | | | Mol File: | 14279-91-5.mol |  |
| | 4-Chlorophenylguanidine hydrochloride Chemical Properties |
| Melting point | 237-238 °C(Solv: water (7732-18-5)) | | storage temp. | Store at RT | | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) | | form | Solid | | color | White to Pale Green | | Water Solubility | Soluble to 100 mM in water |
| | 4-Chlorophenylguanidine hydrochloride Usage And Synthesis |
| Uses | p-Chlorophenylguanidine Hydrochloride is an reagent used in the synthesis of pyrimidine derivatives as hSMG-1 inhibitors, potential targets for cancer treatment. | | Biological Activity | 4-chlorophenylguanidine hydrochloride is a potent and selective inhibitor of urokinase [1].urokinase is a serine protease. its primary physiological substrate is plasminogen, which is an inactive form of plasmin. urokinase plays an important role in vascular diseases and cancer.4-chlorophenylguanidine hydrochloride inhibited urokinase and trypsin with ki value of 6.07 μm and 120 μm, respectively [1]. | | storage | Store at RT | | references | [1]. yang h, henkin j, kim kh, et al. selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. j med chem, 1990, 33(11): 2956-2961. |
| | 4-Chlorophenylguanidine hydrochloride Preparation Products And Raw materials |
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