NQO1 substrate manufacturers
- NQO1 substrate
-
- $38.00
-
2026-07-27
- CAS:2304503-05-5
- Purity: 98.02%
- Supply Ability: 10g
- NQO1 substrate
-
- $38.00
-
2026-07-27
- CAS:2304503-05-5
- Purity: 98.02%
- Supply Ability: 10g
|
| | NQO1 substrate Basic information |
| Product Name: | NQO1 substrate | | Synonyms: | NQO1 substrate;9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 6,7-difluoro-9-oxo-;NQO-1 substrate|||NQO1 substrate;NQO1 substrate, 10 mM in DMSO | | CAS: | 2304503-05-5 | | MF: | C13H2F2N4O | | MW: | 268.18 | | EINECS: | | | Product Categories: | | | Mol File: | 2304503-05-5.mol |  |
| | NQO1 substrate Chemical Properties |
| Boiling point | 593.0±50.0 °C(Predicted) | | density | 1.69±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 125 mg/mL (466.10 mM) | | pka | -10.35±0.20(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | NQO1 substrate Usage And Synthesis |
| Uses | NQO1 substrate acts as an efficient NQO1 substrate and may be a new option for the treatment of NQO1-overexpresssing drug-resistant NSCLC[1]. | | References | [1] Wu X, et al. Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer. J Med Chem. 2018 Dec 27;61(24):11280-11297. DOI:10.1021/acs.jmedchem.8b01424 |
| | NQO1 substrate Preparation Products And Raw materials |
|