1H-Indole-3-acetonitrile, α-(5-isoquinolinylmethylene)-, (αZ)-

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1H-Indole-3-acetonitrile, α-(5-isoquinolinylmethylene)-, (αZ)- manufacturers

  • PIP4K-IN-a131
  • PIP4K-IN-a131 pictures
  • $650.00
  • 2026-07-15
  • CAS:2055405-95-1
  • Purity:
  • Supply Ability: 10g
  • PIP4K-IN-a131
  • PIP4K-IN-a131 pictures
  • $247.00
  • 2025-10-28
  • CAS:2055405-95-1
  • Purity:
  • Supply Ability: 10g
1H-Indole-3-acetonitrile, α-(5-isoquinolinylmethylene)-, (αZ)- Basic information
Product Name:1H-Indole-3-acetonitrile, α-(5-isoquinolinylmethylene)-, (αZ)-
Synonyms:1H-Indole-3-acetonitrile, α-(5-isoquinolinylmethylene)-, (αZ)-;PIP4K-IN-a131
CAS:2055405-95-1
MF:C20 H13 N3
MW:295.34
EINECS:
Product Categories:
Mol File:2055405-95-1.mol
1H-Indole-3-acetonitrile, α-(5-isoquinolinylmethylene)-, (αZ)- Structure
1H-Indole-3-acetonitrile, α-(5-isoquinolinylmethylene)-, (αZ)- Chemical Properties
Boiling point 562.2±45.0 °C(Predicted)
density 1.308±0.06 g/cm3(Predicted)
pka16.75±0.30(Predicted)
form Solid
color Light yellow to yellow
Safety Information
MSDS Information
1H-Indole-3-acetonitrile, α-(5-isoquinolinylmethylene)-, (αZ)- Usage And Synthesis
UsesPIP4K-IN-a131 is PIP4K lipid kinases inhibitor, with IC50s of 1.9 μM and 0.6 μM for purified PIP4K2A and PIP4Ks, respectively. PIP4K-IN-a131 exhibits cancer-selective lethality via dual blockade of the lipid kinase PIP4Ks and mitotic pathways[1].
References[1] Mayumi Kitagawa, et al. Dual Blockade of the Lipid Kinase PIP4Ks and Mitotic Pathways Leads to Cancer-Selective Lethality. Nat Commun. 2017 Dec 19;8(1):2200. DOI:10.1038/s41467-017-02287-5
1H-Indole-3-acetonitrile, α-(5-isoquinolinylmethylene)-, (αZ)- Preparation Products And Raw materials
Tag:1H-Indole-3-acetonitrile, α-(5-isoquinolinylmethylene)-, (αZ)-(2055405-95-1) Related Product Information
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