1H-Indene-5,6-diol, 1-nonylidene-3-(trifluoromethyl)-

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1H-Indene-5,6-diol, 1-nonylidene-3-(trifluoromethyl)- manufacturers

  • (E/Z)-E64FC26
  • (E/Z)-E64FC26 pictures
  • 2026-07-14
  • CAS:2285446-67-3
  • Purity: 98.23%
  • Supply Ability: 10g
1H-Indene-5,6-diol, 1-nonylidene-3-(trifluoromethyl)- Basic information
Product Name:1H-Indene-5,6-diol, 1-nonylidene-3-(trifluoromethyl)-
Synonyms:(E/Z)-E64FC26;1H-Indene-5,6-diol, 1-nonylidene-3-(trifluoromethyl)-
CAS:2285446-67-3
MF:C19H23F3O2
MW:340.38
EINECS:
Product Categories:
Mol File:2285446-67-3.mol
1H-Indene-5,6-diol, 1-nonylidene-3-(trifluoromethyl)- Structure
1H-Indene-5,6-diol, 1-nonylidene-3-(trifluoromethyl)- Chemical Properties
Boiling point 423.0±45.0 °C(Predicted)
density 1.249±0.06 g/cm3(Predicted)
pka8.73±0.20(Predicted)
form Solid
color Light yellow to yellow
Safety Information
MSDS Information
1H-Indene-5,6-diol, 1-nonylidene-3-(trifluoromethyl)- Usage And Synthesis
Uses(E/Z)-E64FC26 is a mixture complex of E-E64FC26 and Z-E64FC26. E64FC26 (E-E64FC26) is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6. E64FC26 shows anti-myeloma activity[1][2].
References[1] Nathan G. Dolloff, et al. Indene derivatives and uses thereof. US20190062298A1.
[2] Robinson RM, et al. Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma. Leukemia. 2019 Apr;33(4):1011-1022. DOI:10.1038/s41375-018-0263-1
1H-Indene-5,6-diol, 1-nonylidene-3-(trifluoromethyl)- Preparation Products And Raw materials
Tag:1H-Indene-5,6-diol, 1-nonylidene-3-(trifluoromethyl)-(2285446-67-3) Related Product Information
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