| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
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| Tel: |
021-50460086-9 15921403865 |
| Email: |
han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:2-(2,6-Dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione
CAS:2222114-22-7
Purity:95%HPLC Package:250MG;1G Remarks:211949
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| Company Name: |
Beijing Yisiyan Technology Research Center
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| Tel: |
010-56645598 13366904824; |
| Email: |
bjkaida@163.com |
| Products Intro: |
Product Name:1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)-
CAS:2222114-22-7
Package:100mg/;500mg/;1000mg/;5000mg/
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| Company Name: |
ShangHai Angti Biotechnology Co., Ltd.
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| Tel: |
13764913901 |
| Email: |
info@angtibio.com |
| Products Intro: |
Product Name:2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione
CAS:2222114-22-7
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1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)- manufacturers
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| | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)- Basic information |
| Product Name: | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)- | | Synonyms: | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)-;Thalidomide-Piperazine 5-fluoride;2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione;2-(2,6-Dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione , Thalidomide-Piperazine 5-fluoride;2-(2,6-Dioxo-3-piperidyl)-5-fluoro-6-(1-piperazinyl)isoindoline-1,3-dione;2-(2,6-Dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)-1H-isoindole-1,3(2H)-dione;2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione | | CAS: | 2222114-22-7 | | MF: | C17H17FN4O4 | | MW: | 360.34 | | EINECS: | | | Product Categories: | chem-chemical | | Mol File: | 2222114-22-7.mol |  |
| | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)- Chemical Properties |
| Boiling point | 652.2±55.0 °C(Predicted) | | density | 1.475±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, protect from light | | form | Solid | | pka | 10.59±0.40(Predicted) | | color | Off-white to light green |
| | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)- Usage And Synthesis |
| Uses | Thalidomide-Piperazine 5-fluoride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. | | IC 50 | Cereblon | | References | [1] Hexiang Wang, et al. Degradation of androgen receptor (ar) by conjugation of ar antagonists with e3 ligase ligand and methods of use. WO2021058017A1. |
| | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-6-(1-piperazinyl)- Preparation Products And Raw materials |
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