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2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride

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2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride Suppliers list
Company Name: HANGZHOU LAURET BIOTECHOLOGY CO.,LTD  Gold
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2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride manufacturers
2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride Basic information
Product Name:2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
Synonyms:2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride;Thalidomide-piperazine (hydrochloride);2-(2,6-Dioxopiperidin-3-yl)-5-(piperazin-1-yl)isoindoline-1,3-dione hydrochloride;2-(2,6-dioxo-3-piperidyl)-5-piperazin-1-yl-isoindoline-1,3-dione;Thalidomide-5'-piperazine, HCl salt;Thalidomide-5-piperazine HCl;Pomalidomide 5'-piperazine;2-(2,6-Dioxo-3-piperidinyl)-5-(1-piperazinyl)isoindoline-1,3-dione Hydrochloride
CAS:2228029-82-9
MF:C17H19ClN4O4
MW:378.81
EINECS:
Product Categories:
Mol File:2228029-82-9.mol
2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride Structure
2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride Chemical Properties
storage temp. 4°C, away from moisture
form powder
color Light yellow to green yellow
InChIKeyGFCKACFUYUKAPW-UHFFFAOYSA-N
SMILESO=C1N(C2CCC(NC2=O)=O)C(C3=CC=C(N4CCNCC4)C=C31)=O
Safety Information
WGK Germany WGK 3
Storage Class6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard ClassificationsRepr. 1B
MSDS Information
2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride Usage And Synthesis
UsesThalidomide-piperazine hydrochloride has the potential for the research of leprosy and multiple myeloma. Thalidomide-piperazine hydrochloride used as a tool in developmental biology leads to important discoveries in the biochemical pathways of limb development[1].
Biological ActivityThalidomide-piperazine hydrochloride has the potential for the research of leprosy and multiple myeloma. Thalidomide-piperazine hydrochloride used as a tool in developmental biology leads to important discoveries in the biochemical pathways of limb development[1].
IC 50Cereblon
storageStore at -20°C
References[1]. Kim JH, et al. Thalidomide: the tragedy of birth defects and the effective treatment of disease [published correction appears in Toxicol Sci. 2012 Feb;125(2):613]. Toxicol Sci. 2011;122(1):1-6.
2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride Preparation Products And Raw materials
Raw materialsPiperazine-->2H-Isoindole
Preparation ProductsThalidomide-->Pomalidomide
Tag:2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride(2228029-82-9) Related Product Information
L-Prolinamide, β-alanyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- (S)-tert-butyl 2-((1R,2R)-3-((1S,2R)-1-hydroxy-1-phenylpropan-2-ylamino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate (S,R,S)-AHPC-PEG2-acid Mal-PEG8-acid 1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-(1-piperazinyl)-, hydrochloride (1:2)