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| | (1R,2S,4S,5S)-4-[2-Iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanol dihydrogen phosphate ester tetraammonium salt Basic information |
| Product Name: | (1R,2S,4S,5S)-4-[2-Iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanol dihydrogen phosphate ester tetraammonium salt | | Synonyms: | MRS 2500 TETRAAMMONIUM SALT;(1R*,2S*)-4-[2-Iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanoldihydrogenphosphateestertetraammoniumsalt;[(1R,2S,4S,5S)-4-[2-iodo-6-(methylamino)purin-9-yl]-2-phosphonooxy-1-bicyclo[3.1.0]hexanyl]methyl dihydrogen phosphate;MRS 2500 , CID: 44448831;Bicyclo[3.1.0]hexane-1-methanol, 4-[2-iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)-, 1-(dihydrogen phosphate), (1R,2S,4S,5S)-;MRS 2500 tetraammoni;(1R,2S,4S,5S)-4-[2-Iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanol dihydrogen phosphate ester tetraammonium salt | | CAS: | 779323-43-2 | | MF: | C13H18IN5O8P2 | | MW: | 561.16 | | EINECS: | | | Product Categories: | | | Mol File: | 779323-43-2.mol | ![(1R,2S,4S,5S)-4-[2-Iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanol dihydrogen phosphate ester tetraammonium salt Structure](CAS/GIF/779323-43-2.gif) |
| | (1R,2S,4S,5S)-4-[2-Iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanol dihydrogen phosphate ester tetraammonium salt Chemical Properties |
| Boiling point | 878.177±75.00 °C(Press: 760.00 Torr)(predicted) | | density | 2.586±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | Store at -20°C | | pka | 1.894±0.10(predicted) | | Water Solubility | <56.12mg/ml in Water |
| | (1R,2S,4S,5S)-4-[2-Iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanol dihydrogen phosphate ester tetraammonium salt Usage And Synthesis |
| Uses | MRS 2500 tetraammonium salt is a highly potent and selective antagonist of the platelet P2Y1 receptor. It inhibits ADP-induced aggregation of human platelets. | | Biological Activity | Highly potent and selective antagonist of the platelet P2Y 1 receptor (K i = 0.78 nM). Inhibits ADP-induced aggregation of human platelets with an IC 50 value of 0.95 nM. Prevents thrombus formation in vivo . |
| | (1R,2S,4S,5S)-4-[2-Iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanol dihydrogen phosphate ester tetraammonium salt Preparation Products And Raw materials |
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