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1,7-Diaza-spiro[4.5]decane-7-carboxylic acid tert-butyl ester

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1,7-Diaza-spiro[4.5]decane-7-carboxylic acid tert-butyl ester Basic information
Product Name:1,7-Diaza-spiro[4.5]decane-7-carboxylic acid tert-butyl ester
Synonyms:1,7-Diazaspiro[4.5]decane-7-carboxylic acid, 1,1-dimethylethyl ester;1,7-Diaza-spiro[4.5]decan...;1,7-Diazaspiro[4.5]decane-7-carboxylic acid tert-butyl ester - D5999;tert-butyl 1,9-diazaspiro[4.5]decane-9-carboxylate;1,7-diazaspiro[4.5]decylalkane-7-macetic acidtertbutyl ester;tert-butyl 1,7-diazaspiro[4.5]decane-7-carboxylate;1,7-Diaza-spiro[4.5]decane-7-carboxylic acid tert-butyl ester
CAS:939793-21-2
MF:C13H24N2O2
MW:240.34
EINECS:
Product Categories:
Mol File:939793-21-2.mol
1,7-Diaza-spiro[4.5]decane-7-carboxylic acid tert-butyl ester Structure
1,7-Diaza-spiro[4.5]decane-7-carboxylic acid tert-butyl ester Chemical Properties
storage temp. 2-8°C(protect from light)
AppearanceColorless to light yellow Liquid
InChIInChI=1S/C13H24N2O2/c1-12(2,3)17-11(16)15-9-5-7-13(10-15)6-4-8-14-13/h14H,4-10H2,1-3H3
InChIKeyPDFULYHFVRJQJO-UHFFFAOYSA-N
SMILESN1C2(CCCN(C(OC(C)(C)C)=O)C2)CCC1
Safety Information
HS Code 2933998090
MSDS Information
1,7-Diaza-spiro[4.5]decane-7-carboxylic acid tert-butyl ester Usage And Synthesis
Usestert-Butyl-1,7-diazaspiro[4.5]decane-7-carboxylate is a useful reagent in preparation of spiro heterocycles as phosphodiesterase inhibitors.
Pharmaceutical ApplicationsThe major structure of 1,7-DIAZA-SPIRO[4.5]DECANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER, Spiro[4.5]decane, functions as a key intermediate in organic synthesis, particularly for the preparation of pharmaceutical derivatives. For instance, it has been employed in the synthesis of spiro[4.5]decane-based analogues of 1α,25-dihydroxyvitamin D3, which exhibit potential biological activity relevant to therapeutic applications.[1]
References[1] Synthesis of Spiro[4.5]decane CF-Ring Analogues of 1α,25-Dihydroxyvitamin D3. Org. Lett. 2006, 8, 19, 4247–4250. DOI:10.1021/ol061575p
1,7-Diaza-spiro[4.5]decane-7-carboxylic acid tert-butyl ester Preparation Products And Raw materials
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