| Company Name: |
Hy Gro Chemicals Pharmtek Pvt Ltd
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+91-9100059638 +91-9666123049 |
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hygro@hygrochemicals.com |
| Products Intro: |
Product Name:Phenyramidol hydrochloride
CAS:326-43-2
Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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| Company Name: |
Global Calcium Pvt Ltd
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| Tel: |
+91-8050750904 +91-8040554500 |
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info@globalcalcium.com |
| Products Intro: |
Product Name:Phenyramidol hydrochloride
CAS:326-43-2
Purity:99% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride manufacturers
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| | alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride Basic information |
| Product Name: | alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride | | Synonyms: | alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride;FENYRAMIDOLHYDROCHLORIDE;Firmalgil;Phenyramidol HCl;Vazalmin;1-Phenyl-2-(pyridin-2-ylamino)ethanol hydrochloride;Benzenemethanol, a-[(2-pyridinylamino)methyl]-,hydrochloride (1:1) | | CAS: | 326-43-2 | | MF: | C13H15ClN2O | | MW: | 250.724 | | EINECS: | 2063083 | | Product Categories: | | | Mol File: | 326-43-2.mol | ![alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride Structure](CAS/GIF/326-43-2.gif) |
| | alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride Chemical Properties |
| Toxicity | LD50 oral in mouse: 2425mg/kg |
| | alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride Usage And Synthesis |
| Originator | Analexin, Mallinckrodt Inc., US ,1960 | | Uses | Analgesic; relaxant
(skeletal muscle). | | Manufacturing Process | A mixture containing 188 g (0.20 mol) of 2-arninopyridine, 0.55 g of lithium amide and 75 cc of anhydrous toluene was refluxed for 1.5 hours. Styrene oxide (12.0 g = 0.10 mol) was then added to the reaction mixture with stirring over a period of ten minutes. The reaction mixture was stirred and refluxed for an additional 3.5 hours. A crystalline precipitate was formed during the reaction which was removed by filtration, MP 170°C to 171°C. 1.5 g. The filtrate was concentrated to dryness and a dark residue remained which was crystallized from anhydrous ether; yield 6.0 g. Upon recrystallization of the crude solid from 30 cc of isopropyl alcohol, 2.0 g of a light yellow solid was isolated; MP 170° to 171°C. | | Therapeutic Function | Analgesic, Muscle relaxant |
| | alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride Preparation Products And Raw materials |
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