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| | (2,3-dihydroxypropyl)trimethylammonium chloride Basic information |
| Product Name: | (2,3-dihydroxypropyl)trimethylammonium chloride | | Synonyms: | (2,3-dihydroxypropyl)trimethylammonium chloride;1-Propanaminium, 2,3-dihydroxy-N,N,N-trimethyl-, chloride;(2,3-DIHYDROXYPROPYL)TRIMETHYLAMMONIUM CHLORIDE (DHPTAC) ;1-Propanaminium, 2,3-dihydroxy-N,N,N-trimethyl-, chloride (1:1);Levocarnitine Impurity 26;(2,3-Dihydroxypropyl)trimethylammoniumchlorid;N-[(2,3-dihydroxy)prop-1-yl]-N,N,N-trimethylammonium chloride;Levocarnitine Impurity 10 Chloride | | CAS: | 34004-36-9 | | MF: | C6H16ClNO2 | | MW: | 169.64974 | | EINECS: | 251-783-2 | | Product Categories: | | | Mol File: | 34004-36-9.mol |  |
| | (2,3-dihydroxypropyl)trimethylammonium chloride Chemical Properties |
| | (2,3-dihydroxypropyl)trimethylammonium chloride Usage And Synthesis |
| Uses | Dihydroxypropyltrimonium Chloride is a useful research chemical compound used in the synthesisof amine-functionalized branched polyethyleneimines with specific adhesion properties for surface modification. | | Synthesis | General procedure for the synthesis of 2,3-dihydroxypropyl-trimethylammonium chloride from 3-chloro-1,2-propanediol and trimethylamine: 0.00 g (±)-3-chloro-1,2-propanediol (0.452 mol), 178.00 g of a 30% aqueous solution of trimethylamine (0.904 mol), and 50 mL of deionized water were added to a 500 mL three-neck flask. Subsequently, the reaction system was warmed to 90 °C and stirred continuously at this temperature for 16 hours to ensure complete reaction of 3-chloro-1,2-propanediol. Upon completion of the reaction, the reaction mixture was cooled to 20 °C and extracted three times with ethyl acetate (100 mL x 3) to remove organic impurities. The aqueous phase was collected and concentrated to dryness by rotary evaporator to give 70.00 g of white solid product in 91.2% yield and 93.40% purity by HPLC. | | References | [1] Patent: CN108129338, 2018, A. Location in patent: Paragraph 0027; 0029; 0030
[2] Annales de Chimie (Cachan, France), 1879, vol. <5> 17, p. 114
[3] Chemische Berichte, 1869, vol. 2, p. 187
[4] Justus Liebigs Annalen der Chemie, 1904, vol. 337, p. 102 |
| | (2,3-dihydroxypropyl)trimethylammonium chloride Preparation Products And Raw materials |
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