(R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate manufacturers
- GR103545
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- $89.00
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2026-05-11
- CAS:126766-43-6
- Purity: 99.75%
- Supply Ability: 10g
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| | (R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate Basic information |
| Product Name: | (R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate | | Synonyms: | (R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate;(R)-(-)-GR103545 fumarate;Inhibitor,Opioid Receptor,imaging,GR103545,inhibit,κ-OR,GR 103545,κ-opioid receptor,GR-103545;GR-103545 fumarate;GR103545, 10 mM in DMSO;1-Piperazinecarboxylic acid,4-[(3,4-dichlorophenyl)acetyl]-3-(1- pyrrolidinylmethyl)-,methyl ester,(3R)-,(2E)-2-butenedioate (1:1) | | CAS: | 126766-43-6 | | MF: | C23H29Cl2N3O7 | | MW: | 530.4 | | EINECS: | | | Product Categories: | | | Mol File: | 126766-43-6.mol |  |
| | (R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate Chemical Properties |
| | (R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate Usage And Synthesis |
| Description | GR-103545 is a reference and non-radio labeled agent. The radio-labeled 11C-GR103545 is a promising PET radiotracer for imaging the κ-OR. | | Uses | GR103545 is a potent and selective agonist of the κ-opioid receptor (κ-OR). 11GR103545 is a radiotracer for imaging κ-OR in vivo[1][2]. | | References | [1] Hayes AG, et, al. A series of novel, highly potent and selective agonists for the kappa-opioid receptor. Br J Pharmacol. 1990 Dec;101(4):944-8. DOI:10.1111/j.1476-5381.1990.tb14185.x [2] Talbot PS, et, al. 11C-GR103545, a radiotracer for imaging kappa-opioid receptors in vivo with PET: synthesis and evaluation in baboons. J Nucl Med. 2005 Mar;46(3):484-94. PMID:15750163 |
| | (R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate Preparation Products And Raw materials |
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