| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Jun9-72-2 CAS:2657659-42-0 Package:10mg;50mg
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
800-364-9897 |
| Email: |
sales@caymanchem.com |
| Products Intro: |
Product Name:Jun9-72-2
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| Company Name: |
Focus Biomolecules
|
| Tel: |
855-362-8721 |
| Email: |
sales@focusbiomolecules.com |
| Products Intro: |
Product Name:Jun9-72-2 CAS:2657659-42-0 Purity:>98% HPLCNMR (Conforms) Package:$75.00/5mg;$275.00/25mg;
|
| Company Name: |
Neobioscience Co., Ltd.
|
| Tel: |
4006-800-892 |
| Email: |
info@neobioscience.com |
| Products Intro: |
Product Name:Jun9-72-2
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| | Phenol, 4-[[methyl[(1R)-1-(1-naphthalenyl)ethyl]amino]methyl]- Basic information |
| | Phenol, 4-[[methyl[(1R)-1-(1-naphthalenyl)ethyl]amino]methyl]- Chemical Properties |
| Boiling point | 435.2±25.0 °C(Predicted) | | density | 1.135±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in DMSO (>30 mg/ml) | | pka | 9.86±0.15(Predicted) | | form | solid | | color | White | | Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| | Phenol, 4-[[methyl[(1R)-1-(1-naphthalenyl)ethyl]amino]methyl]- Usage And Synthesis |
| Description | Jun9-72-2 (CAS 2657659-42-0) is potent inhibitor (IC50 = 670 nM) of SARS-CoV2 papain-like (PL) protease. It showed potent antiviral activity in both Vero E6 (EC50 = 6.62 μM) and Caco2-hACE2 (EC50 = 7.90 μM) cell lines. | | Uses | Jun9-72-2 is a papain (Plpro) inhibitor of SARS-CoV-2 with an IC50 value of 0.67 μM. Jun9-72-2 has antiviral activity[1]. | | References | 1.Ma et al. (2021), Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay; ACS Cent. Sci., 7 1245 |
| | Phenol, 4-[[methyl[(1R)-1-(1-naphthalenyl)ethyl]amino]methyl]- Preparation Products And Raw materials |
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